... plate, consistent with a cell-autonomous disturbance of convergent extension. Inhibitor studies in whole-embryo culture demonstrated a requirement for signalling via RhoA-Rho kinase, but not jun N-terminal kinase, in convergent extension and the onset of neural tube closure. These findings identify...

... the neural tube to the developing heart. A cardiac neural crest lineage is also known to exist in mammals, although detailed information on its axial level of origin and migratory pattern are lacking. We used focal cell labelling and orthotopic grafting, followed by whole embryo culture, to determine...

.... Curr. Biol. 9 , 946 -954. Jones, E. A., Crotty, D., Kulesa, P. M., Waters, C. W., Baron,M. H., Fraser, S. E. and Dickinson, M. E. ( 2002 ). Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture. Genesis 34 , 228 -235. Kimura, C., Yoshinaga, K., Tian, E...

... to be regulated by another notochordal factor. Attachment of surface ectoderm cells to the neural plate is required for dorsolateral bending, which ensures neural tube closure in the absence of sonic hedgehog signaling. Neurulation Neural plate Morphogenesis Embryo culture Notochord patched...

... phenotype is strikingly different from that of embryos lacking RARα and RARβ (Aα/Aβmutants), in which we have previously shown that the territory corresponding to R5 and R6 is markedly enlarged. Administration of a pan-RAR antagonist at E8.0 to wild-type embryos cultured in vitro results in an Aα/Aβ-like...

... , 7649 – 7660 . 10.1523/JNEUROSCI.16-23-07649.1996 Van Maele-Fabry , G. , Clotman , F. , Gofflot , F. , Bosschaert , J. and Picard , J. J. ( 1997 ). Postimplantation mouse embryos cultured in vitro. Assessment with whole-mount immunostaining and in situ hybridisation...

... Bone morphogenetic protein 2 (BMP2) Cardiac progenitor cell Embryo culture In situ hybridization Intercalated disc Cadherin signaling Cardiac progenitor cells originate from the rostral half of the primitive streak and form a pair of heart-forming fields within lateral plate mesoderm...

... with continued normal fetal development in vivo. * Author for correspondence 26 01 1995 © 1995 by Company of Biologists 1995 macrophage colony-stimulating factor CSF-1 blastocyst trophoblast cell preimplantation development embryo culture Several receptors that recognize...

... flexures in chicken embryo . Develop. Growth and Differ . 29 , 497 – 502 . 10.1111/j.1440-169X.1987.00497.x © 1991 by Company of Biologists 1991 neural tube morphogenesis mouse mutant embryo culture curvature curly tail ( ct ) The process of neurulation, by which...

... 02139, USA © 1990 by Company of Biologists 1990 Moloney Murine Leukemia Virus mouse embryo Lac Z expressing vector long terminal repeat embryo culture Studies of host-virus relationships during embryogen esis have been stimulated by the hope that the molecu lar control...

... microinjected orthotopically into host embryos of the same developmental stage except for area 1 (forebrain) grafts which were, for technical reasons, injected into area 2. After various periods of time in whole embryo culture, the embryos were examined by immunohistochemical staining in order to determine...

... cysteine proteinases, specifically inhibited by leupeptin, are of paramount importance in this yolk sac function. 06 11 1984 Copyright © 1985 by Company of Biologists 1985 Rat embryo embryo culture cathepsins proteolysis yolk sac teratogenesis In a series of papers, Freeman...