1-20 of 115
Keywords: embryo
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2023) 150 (1): dev201173.
Published: 5 January 2023
... Embryo Endothelial cell Haematopoietic stem cell Haemogenic endothelial cell Fondation pour la Recherche Médicale http://dx.doi.org/10.13039/501100002915 Institut National de la Santé et de la Recherche Médicale http://dx.doi.org/10.13039/501100001677 Centre National...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (1): dev201145.
Published: 5 January 2023
... microtubules. Recruitment of SAC proteins to unattached kinetochores generates an inhibitory signal that prolongs mitotic duration. Chordate embryos are atypical in that spindle defects do not delay mitotic progression during early development, implying that either the SAC is inactive or the cell-cycle target...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (23): dev200298.
Published: 29 November 2022
... at the presomitic to the 3-somite stage in the avian embryo . Development 103 , 101 - 113 . 10.1242/dev.103.Supplement.101 Dhouailly , D. ( 1973 ). Dermo-epidermal interactions between birds and mammals: differentiation of cutaneous appendages . J. Embryol. Exp. Morphol. 30 , 587 - 603...
Journal Articles
In collection:
Plant development
Journal: Development
Development (2022) 149 (21): dev200917.
Published: 21 October 2022
... moellendorffii (SmBRX) in an A. thaliana wild-type background confers robustly enhanced root growth vigor that persists throughout the life cycle. This effect can be traced to a substantial increase in seed and embryo size, is associated with enhanced vascular tissue proliferation, and can be reproduced...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (16): dev200765.
Published: 18 August 2022
... by The Company of Biologists Ltd 2022 Summary: This Review presents the intrinsic and extrinsic mechanical forces acting on the embryonic gut and their determining role in structuring the development of this organ. Biomechanics Intestine Embryo Mouse Chicken Human Université de Paris...
Journal Articles
Journal: Development
Development (2022) 149 (15): dev200331.
Published: 29 July 2022
... in utero injection into mouse embryos . Proc. Natl. Acad. Sci. USA 113 , 1570 - 1575 . 10.1073/pnas.1525518113 Cohen , M. A. , Zhang , S. , Sengupta , S. , Ma , H. , Bell , G. W. , Horton , B. , Sharma , B. , George , R. E. , Spranger , S. and Jaenisch...
Journal Articles
Journal: Development
Development (2022) 149 (14): dev200356.
Published: 14 July 2022
..., applying staging criterion is challenging, even for experts. When designing experiments, researchers can either wait until an easy-to-determine stage is reached, or halt experiments at a set time point and then ‘stage’ the embryos. Our Landmarks Table ( Table S1 ) provides a succinct guide that can be used...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (11): dev200854.
Published: 6 June 2022
... reprogramming contributes significantly to the dynamic gene expression during ZGA; however, the mechanism has yet to be resolved. Here, we find histone deacetylases 1 and 2 (HDAC1/2) can regulate ZGA through lysine deacetylase activity. Notably, in mouse embryos, overexpression of a HDAC1/2 dominant-negative...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (10): dev200351.
Published: 26 May 2022
...Ming-Zhe Dong; Ying-Chun Ouyang; Shi-Cai Gao; Xue-Shan Ma; Yi Hou; Heide Schatten; Zhen-Bo Wang; Qing-Yuan Sun ABSTRACT Mammalian early embryo cells have complex DNA repair mechanisms to maintain genomic integrity, and homologous recombination (HR) plays the main role in response to double-strand...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2022) 149 (7): dev198341.
Published: 14 April 2022
... reproduction. Despite our knowledge of mitotic mis-segregation in somatic cells, the molecular pathways regulating chromosome fidelity during the error-prone cleavage-stage of mammalian embryogenesis remain largely undefined. Using bovine embryos and live-cell fluorescent imaging, we observed frequent micro...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (6): dev199743.
Published: 23 March 2022
... to implantation. Unfortunately, our understanding of these key processes for embryo survival is limited because current culture systems cannot sustain ungulate embryo development beyond hatching . Here, we report a culture system that recapitulates most developmental landmarks of gastrulating ovine embryos...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (24): dev200191.
Published: 21 December 2021
... and transcriptome analyses of two-cell embryos revealed that, although ZGA took place, there were subtle defects in embryos that lacked maternal Dppa2/4. Strikingly, heterozygous offspring that inherited the null allele maternally had higher preweaning lethality than those that inherited the null allele paternally...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200059.
Published: 15 December 2021
... is the prime organizing center for axial elongation in mouse embryos. The T-box transcription factor brachyury (T) is essential for both formation of the notochord and maintenance of NMPs, and thus is a key regulator of trunk and tail development. The T promoter controlling T expression in NMPs and nascent...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2021) 148 (13): dev199589.
Published: 6 July 2021
... surrounding non-embryonic tissues . We have coupled fluorescence-activated nuclei sorting together with single-nucleus mRNA-sequencing to construct a gene expression atlas of Arabidopsis thaliana early embryos at single-cell resolution. In addition to characterizing cell-specific transcriptomes, we found...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2021) 148 (8): dev198150.
Published: 16 April 2021
... determination occurs after PGC colonization of the gonads, and that germ cell tumors reflect a failure of this process. Determination Embryo Germ cell tumor Germline Potency Primordial germ cell The germline is the cell lineage, from zygote to gamete, with the capacity or potential...
Journal Articles
Journal: Development
Development (2021) 148 (18): dev192955.
Published: 24 March 2021
...-computed tomography (micro-CT), have been incorporated into the high-throughput embryo pipeline of the International Mouse Phenotyping Consortium (IMPC). This project generates large volumes of raw data that cannot be immediately exploited without significant resources of personnel and expertise. Thus...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (6): dev189217.
Published: 15 March 2021
... marks a stage of developmental divergence between key model organisms, and thus potential variance in the cell and molecular mechanisms for PGC specification. In humans, PGC specification is very difficult to study in vivo . To address this, the combined use of human and nonhuman primate embryos...
Journal Articles
Journal: Development
Development (2021) 148 (5): dev188490.
Published: 12 March 2021
... and developmental functions of TGFβ family proteins. BMP Development Embryo Nodal TGFβ Transforming growth factor β (TGFβ) was first discovered in the late 1970s as a secreted polypeptide growth factor with the ability to transform mammalian fibroblasts ( Moses et al., 2016 ). Since...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (22): dev190728.
Published: 30 November 2020
... activity. Here, we establish an inactive mR3-based non-engineered mR3/dsRNA system for RNA tracking in zebrafish embryos. In vitro binding experiments show that inactive Staphylococcus epidermidis mR3 (dSmR3) protein possesses the highest binding affinity with dsRNAs among mR3s from other related species...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (10): dev175596.
Published: 28 May 2020
... Embryo Migration Adhesion Differentiation Biophysical The extracellular matrix (ECM) is essential for metazoan life; without it, we would be merely an amorphous mass of cells. The ECM is the non-cellular component of all tissues, forming the physical environment surrounding cells, and playing...