... for the absence of AER anteriorly. As the AER is required to maintain the underlying mesenchyme( Dudley et al., 2002 ), this would lead, at later stages, to the loss of anterior mesenchyme and truncation of the anterior skeleton elements. Fig. 4. Dorsoventral specification is altered in the double-null...

... sequence is provided. This suggests that int-2 and eFGF, which possess signal sequences, are better candidates for inducing factors in vivo than is bFGF. Copyright © 1992 by Company of Biologists 1992 Xenopus gastrulation mesoderm induction dorsoventral specification anteroposterior...