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Keywords: dorsalization
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Journal Articles
Journal: Development
Development (2017) 144 (11): 2009–2020.
Published: 1 June 2017
...Endika Haro; Billy A. Watson; Jennifer M. Feenstra; Luke Tegeler; Charmaine U. Pira; Subburaman Mohan; Kerby C. Oberg Lmx1b is a homeodomain transcription factor responsible for limb dorsalization. Despite striking double-ventral (loss-of-function) and double-dorsal (gain-of-function) limb...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (13): 2955–2965.
Published: 1 July 1999
...Tobias Roeser; Stefan Stein; Michael Kessel ABSTRACT Studies in Xenopus laevis and zebrafish suggest a key role for β-catenin in the specification of the axis of bilateral symmetry. In these organisms, nuclear β-catenin demarcates the dorsalizing centers. We have asked whether β-catenin plays...
Journal Articles
Journal: Development
Development (1997) 124 (23): 4739–4748.
Published: 1 December 1997
... expression in the marginal zone. Szl can dorsalize Xenopus embryos if expressed after the midblastula transition, strengthening the idea that zygotic expression of wnts and in particular of Xwnt8 plays a role in antagonizing dorsal signals. It also suggests that inhibiting ventralizing wnts parallels...
Journal Articles
Journal Articles
Journal: Development
Development (1995) 121 (11): 3651–3662.
Published: 1 November 1995
...-2 ) are identified and shown to be expressed transiently during embryogenesis, first within the vegetal region of late blastulae and later in the marginal zone during gastrulation, with enrichment in the dorsal lip. Xnr s and mouse nodal function as dosedependent dorsoanterior and ventral mesoderm...
Journal Articles
Journal: Development
Development (1993) 117 (1): 263–271.
Published: 1 January 1993
...Laura A. Lettice; Jonathan M. W. Slack ABSTRACT According to the ‘three signal model’, the regional specification of tissue type within the mesoderm of Xenopus laevis occurs in a process called ‘dorsalization’. We have studied the timing and transmission characteristics of this signal, and assessed...
Journal Articles
Journal Articles
Journal: Development
Development (1988) 103 (3): 581–590.
Published: 1 July 1988
... be solely responsible for inducing the ventral mesoderm and that dorsalization of ventral mesoderm to the level of somitic muscle might be achieved either by a very high local concentration of FGF in the dorsal region, or by the action of a second, synergistic, agent in the dorsal region. 08 04 1988...
Journal Articles
Journal: Development
Development (1988) 102 (4): 677–686.
Published: 1 April 1988
...Chester M. Regen; Richard A. Steinhardt The discovery that lithium treatment at blastula stages can induce axis formation suggested that it might act by respecifying the cytoplasmic rearrangement-generated dorsoventral pattern, so that ventral cells behave like their dorsal counterparts. We have...
Journal Articles
Journal: Development
Development (1987) 100 (2): 279–295.
Published: 1 June 1987
...L. Dale; J. M. W. Slack ABSTRACT We have further analysed the roles of mesoderm induction and dorsalization in the formation of a regionally specified mesoderm in early embryos of Xenopus laevis. First, we have examined the regional specificity of mesoderm induction by isolating single blastomeres...
Journal Articles
Journal: Development
Development (1985) 89 (Supplement): 317–331.
Published: 1 November 1985
... induction occurs in the early blastula and results from the action of vegetal pole cells on the animal hemisphere. At least two mesodermal rudiments are formed, one dorsal and one ventral. During the next interaction, which we call dorsalization , the ventral mesodermal rudiment becomes subdivided...