... suggested a direct role for Myc in regulating growth. We have used dm 4 , a new null allele of the Drosophila diminutive ( dm ) gene, which encodes dMyc on the X chromosome, to investigate a role for dMyc in larval endoreplicating tissues,where cellular growth and DNA replication occur in the absence...

... of the Drosophila homolog of the Myc oncoprotein (dMyc),which is encoded by the dm locus. We carried out mosaic analysis to elucidate the functions of dMyc in the germline and somatic cells of the ovary during oogenesis, a process that involves cell proliferation, differentiation and growth. Germline and somatic...