... distribution of competence is established during gastrulation paralleling the dorsal restriction of neural competence. We further show that Dlx3 and GATA2 are required cell-autonomously for panplacodal and epidermal marker expression in the non-neural ectoderm, while ectopic expression of Dlx3 or GATA2...

...Joonsung Hwang; Taraneh Mehrani; Sarah E. Millar; Maria I. Morasso Dlx homeobox transcription factors regulate epidermal, neural and osteogenic cellular differentiation. Here, we demonstrate the central role of Dlx3 as a crucial transcriptional regulator of hair formation and regeneration...

...-mesenchymal interactions during development. Dlx3 and p63 act as part of the transcriptional regulatory pathways relevant in ectoderm derivatives, and autosomal mutations in either of these genes are associated with human EDs. However, the functional relationship between both proteins is unknown. Here,we...

... but not for its subsequent patterning. We propose that Sox9 is one of the key regulators of inner ear specification in Xenopus . * Author for correspondence (e-mail: saintj@vet.upenn.edu ) 9 1 2004 © 2004. 2004 Sox9 Tbx2 Pax8 Dlx3 Otic placode Inner ear Wnt Fgf Xenopus...

... deletion removes several known genes and expressed sequence tags, including dlx3 and dlx7 , two transcription factors that share a homoeobox domain similar in sequence to the Drosophila Distal-less gene. dlx3 and dlx7 are expressed in an overlapping pattern in the regions that produce the otic...