1-20 of 238
Keywords: development
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal Articles
Journal: Development
Development (2023) 150 (24): dev201974.
Published: 11 December 2023
... in TORC2 loss-of-function mutants, and grd-1 and ptr-11 overexpression delays wild-type development to a similar level to that in TORC2 loss-of-function animals. These findings potentially indicate an unexpected role for grd-1 and ptr-11 in slowing developmental rate downstream of a nutrient-sensing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (22): dev202111.
Published: 9 November 2023
... that the original work is properly attributed. Summary: Multi-omics assays of purified embryonic and in vitro -generated cells identify thousands of notochord enhancers including TNE2, which is essential for notochord function and tail development of the mouse embryo. Mouse Embryo Development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (20): dev201599.
Published: 17 October 2023
... and highlights the roles of individual hormones in regulating growth, cell proliferation and differentiation. IGF Development Insulin National Institutes of Health http://dx.doi.org/10.13039/100000002 1R01DK123433 Nutrient-sensing pathways allow animals to integrate developmental...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (15): dev201830.
Published: 1 August 2023
... Genescu , I. and Garel , S. ( 2021 ). Being superficial: a developmental viewpoint on cortical layer 1 wiring . Curr. Opin. Neurobiol. 66 , 125 - 134 . 10.1016/j.conb.2020.10.003 Gesuita , L. and Karayannis , T. ( 2021 ). A ‘Marginal’ tale: the development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (12): dev201546.
Published: 20 June 2023
... development programs, which posit this mode of transcription as an important feature in developmental gene regulation. In this Review, we present compelling examples of the role of transcriptional bursting in development and explore the question of how stochastic transcription leads to deterministic organism...
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2023) 150 (10): dev201702.
Published: 30 May 2023
...Jan A. Adelmann; Roman Vetter; Dagmar Iber ABSTRACT Tissue patterning during embryonic development is remarkably precise. Here, we numerically determine the impact of the cell diameter, gradient length and the morphogen source on the variability of morphogen gradients. We show that the positional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (3): dev201352.
Published: 10 February 2023
... . Development 147 , dev185421 . 10.1242/dev.185421 Liu , W. , Shaver , T. M. , Balasa , A. , Ljungberg , M. C. , Wang , X. , Wen , S. , Nguyen , H. and Van den Veyver , I. B. ( 2012 ). Deletion of Porcn in mice leads to multiple developmental defects and models...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (3): dev201008.
Published: 2 February 2023
.... Taken together, our work provides a benchmark for 3D MG analysis across MG visualization techniques, developmental ages, and species. Fig. 1. GliaMorph workflow overview. (A) Using global image-level measurements, we developed a tool to quantify 11 different parameters of MG morphology. (B...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (2): dev200436.
Published: 16 January 2023
..., temporal patterning is regulated by the expression of transcription factors referred to as ‘temporal identity’ factors, which control the developmental competence of neural progenitor cells, allowing cell-type production to change as development proceeds ( Brody and Odenwald, 2000 ; Cleary and Doe, 2006...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (24): dev201121.
Published: 23 December 2022
... by microglia is necessary for normal brain development . Science 333 , 1456 - 1458 . 10.1126/science.1202529 Piochon , C. , Kano , M. and Hansel , C. ( 2016 ). LTD-like molecular pathways in developmental synaptic pruning . Nat. Neurosci. 19 , 1299 - 1310 . 10.1038/nn.4389...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (20): dev201004.
Published: 31 October 2022
..., promoting further maturation would enable us to study postnatal development and improve modelling of adult-onset diabetes. Benchmarking the nature of the cells generated in organoids and their maturity will be important to tackle these questions and understand the developmental stages modelled as well...
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (19): dev200986.
Published: 3 October 2022
...-dependent metabolism functionally participates in nephron progenitor maintenance by monitoring pyruvate and proline biogenesis in developing kidneys. * These authors contributed equally to this work ‡ Author for correspondence ( satu.kuure@helsinki.fi ) Handling Editor: Irene Miguel-Aliaga...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (10): dev200446.
Published: 16 May 2022
... physiological Notch signals are not acting to switch cells from self-renewal to differentiation, Notch signals could promote proximal development within a developmental window, defined pharmacologically with γ-secretase inhibitors ( Cheng et al., 2003 , 2007 ). This role would predict that if Notch contributed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (8): dev200270.
Published: 3 May 2022
... with traditional models. Finally, iPSC-derived organoid systems have also become increasingly popular as a tool to study human development and organogenesis, but many of them are lacking in the developmental cues provided by RTMs and, as such, might not be fully representative. It would be interesting to see...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (6): dev200243.
Published: 23 March 2022
..., are enlarged and accumulate massively at the last larval and white prepupal stage ( Rusten et al., 2004 ; Butterworth et al., 1988 ; Butterworth and Forrest, 1984 ). The steroid hormone ecdysone, the master regulator of insect development, drives developmental autophagy in the fat body through downregulation...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (2): dev200118.
Published: 20 January 2022
... are no longer present, with the new methylation pattern itself thus serving as a template of stable cell identity ( Mayran et al., 2018 ; Reizel et al., 2021 ). The process of cell fate determination during development is largely directed by local morphogens, which serve as developmental signals...
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200059.
Published: 15 December 2021
... is the prime organizing center for axial elongation in mouse embryos. The T-box transcription factor brachyury (T) is essential for both formation of the notochord and maintenance of NMPs, and thus is a key regulator of trunk and tail development. The T promoter controlling T expression in NMPs and nascent...
Includes: Supplementary data