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Keywords: daughterless
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (1): dev201366.
Published: 3 January 2023
... the entire Caenorhabditis elegans nervous system. Distinct, lineage-specific proneural class II bHLH factors are generally thought to operate via interaction with a common, class I bHLH subunit, encoded by Daughterless in flies, the E proteins in vertebrates and HLH-2 in C. elegans . To eliminate function...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (11): 2058–2068.
Published: 1 June 2015
... and E2f1 . Here, we show that, in addition to these mechanisms, some Notch signaling is devoted to blocking the growth-suppressing activity of the bHLH DNA-binding protein Daughterless (Da). We demonstrate that Notch signaling activates the expression of extramacrochaetae ( emc ), which encodes a helix...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (10): 2359–2372.
Published: 15 May 2004
.... Drosophila Mesoderm Muscle Subdivision Signaling Transcriptional regulation Notch Suppressor of Hairless bHLH twist daughterless extra machrochaetae Enhancer of split Early in vertebrate and invertebrate development, uncommitted mesodermal cells are patterned into repetitive...
Journal Articles
Journal: Development
Development (2002) 129 (14): 3393–3402.
Published: 15 July 2002
... provide evidence that wingless mediates both effects, at least in part, through repression of the basic helix-loop-helix protein Daughterless. daughterless is required for high proneural gene expression and furrow progression. Ectopic expression of wingless blocks Daughterless expression in the proneural...
Journal Articles
Journal: Development
Development (2002) 129 (13): 3255–3267.
Published: 1 July 2002
...John E. Smith, III; Craig A. Cummings; Claire Cronmiller During Drosophila oogenesis two distinct stem cell populations produce either germline cysts or the somatic cells that surround each cyst and separate each formed follicle. From analyzing daughterless (da) loss-of-function, overexpression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (23): 4705–4714.
Published: 1 December 2001
...John E. Smith, III; Claire Cronmiller As the only class I helix-loop-helix transcription factor in Drosophila , Daughterless (Da) has generally been regarded as a ubiquitously expressed binding partner for other developmentally regulated bHLH transcription factors. From analysis of a novel tissue...
Journal Articles
Journal: Development
Development (2001) 128 (16): 3145–3159.
Published: 15 August 2001
... choice. We find that Twist can form homodimers and heterodimers with the Drosophila E protein homologue, Daughterless,in vitro. Using tethered dimers to assess directly the function of these two particular dimers in vivo, we show that Twist homodimers specify mesoderm and the subsequent allocation...