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Christophe Royer, Karolis Leonavicius, Annemarie Kip, Deborah Fortin, Kirtirupa Nandi, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Shankar Srinivas
Development (2020) 147 (19): dev189449.
Published: 9 October 2020
... with the nuclear localisation of YAP. To test this relationship, we developed several hydrogel-based approaches to alter blastomere geometry in cultured embryos. Unbiased clustering analyses of blastomeres from such embryos revealed that this relationship emerged during compaction. Our results therefore pinpoint...
Includes: Supplementary data
Wilhelmine N. de Vries, Alexei V. Evsikov, Bryce E. Haac, Karen S. Fancher, Andrea E. Holbrook, Rolf Kemler, Davor Solter, Barbara B. Knowles
Development (2004) 131 (18): 4435–4445.
Published: 15 September 2004
.... This suggests that adhesion per se is not essential in the early cleavage stage embryos, that embryos develop normally if compaction does not occur until the morula stage, and that the zona pellucida suffices to maintain blastomere proximity. Although maternal E-cadherin is not essential for the completion...
Hanying Chen, Shu Shi, Lourdes Acosta, Weiming Li, Jonathan Lu, Shideng Bao, Zhuang Chen, Zuocheng Yang, Michael D. Schneider, Kenneth R. Chien, Simon J. Conway, Mervin C. Yoder, Laura S. Haneline, Diego Franco, Weinian Shou
Development (2004) 131 (9): 2219–2231.
Published: 1 May 2004
... and E24-28 in human embryos, is crucial for the developing heart to maintain normal cardiac growth and function in response to an increasing hemodynamic load. Although, ventricular trabeculation and compaction are key morphogenetic events associated with this transition, the molecular and cellular...
Development (1992) 116 (Supplement): 113–118.
Published: 1 April 1992
...David L. Becker; Catherine Leclerc-David; Anne Warner In the mouse embryo, gap junctions first appear at the 8-cell stage as compaction is about to take place. Compaction of the embryo is important for the differentiation of the first two cell types; the inner cell mass and the trophectoderm. Our...
Development (1986) 95 (1): 213–237.
Published: 1 June 1986
...Jeremy B. Levy; Martin H. Johnson; Harry Goodall; Bernard Maro The effect of protein synthesis inhibitors on compaction of the 8-cell mouse embryo has been investigated. The effects observed depended upon the duration and time of drug application and on the features of compaction scored. Continuous...
Development (1985) 90 (1): 311–334.
Published: 1 December 1985
... but separate mechanisms. * C.N.R.S., Paris, France. 24 6 1985 Copyright © 1985 by Company of Biologists 1985 microtubules microfilaments mouse morula compaction polarization taxol nocodazole cytochalasin D /. Embryol. exp. Morph. 90, 311-334 (1985) 311 Printed in Great Britain...
Development (1985) 89 (1): 133–148.
Published: 1 October 1985
...Roger K. W. Smith; Martin H. Johnson The effects of aphidicolin, a reversible inhibitor of DNA polymerase alpha, both on replication and on development of the mouse embryo from the 2- and 4-cell stages to the compacted late 8-cell stage have been assessed. The continuous presence of aphidicolin...