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Keywords: chimaera
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Journal Articles
Journal: Development
Development (2016) 143 (1): 24–34.
Published: 1 January 2016
... a minority of the embryonic stem cell (ESC) inoculum contributes to the adult chimaera. How incoming cells are chosen for integration or elimination remains unclear. By comparing a heterogeneous mix of undifferentiated and differentiating ESCs (serum/LIF) with more homogeneous undifferentiated culture (2i...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1001–1010.
Published: 1 March 2014
.../by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Blastocyst Chimaera Nanog Oct4 (Pou5f1) Primitive endoderm Sox17 A prerequisite for the viviparous development of the mouse embryo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (17): 3499–3510.
Published: 1 September 2013
... ) Competing interests statement The authors declare no competing financial interests. © 2013. Published by The Company of Biologists Ltd 2013 Chimaera Developmental plasticity Regulative development Stochastic gene expression Twin One of the most intriguing observations...
Journal Articles
Journal: Development
Development (2009) 136 (7): 1063–1069.
Published: 1 April 2009
...Ge Guo; Jian Yang; Jennifer Nichols; John Simon Hall; Isobel Eyres; William Mansfield; Austin Smith Mouse embryonic stem (ES) cells derived from pluripotent early epiblast contribute functionally differentiated progeny to all foetal lineages of chimaeras. By contrast, epistem cell (EpiSC) lines...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (8): 1597–1607.
Published: 15 April 2006
... defect of the epiblast cells and is rescued by complementation of NT blastocysts with normal ES or ICM cells. The second type of defect affects growth regulation and the shape of the embryo but does not directly impair the initial establishment of the patterning of the embryo. Only chimaeras formed...
Journal Articles
Journal: Development
Development (1986) 98 (1): 111–121.
Published: 1 November 1986
... content. The receptor cells also degenerate at a slower rate than in the homozygotes. The nature of the interaction resulting in dilution of the retinal lesion in the heterozygous retina was analysed in a series of chimaeras consisting of rds /+ and +/+ genotypes, which also differed in colour genes...
Journal Articles
Journal: Development
Development (1986) 98 (1): 269–285.
Published: 1 November 1986
...Eva S. Rodemer; Alice Ihmer; H. Wartenberg Mesonephric agenesis was achieved by microsurgical excision of the left Wolffian duct and the underlying intermediate mesoderm of different regions between somites 16 and 23 in chickens after 50–52 h of incubation (stage 14 HH). Quail-chick chimaeras were...
Journal Articles
Journal: Development
Development (1986) 98 (1): 99–110.
Published: 1 November 1986
...B. K. Waters; J. Rossant Certain embryonal carcinoma (EC) cell lines can colonize the embryo following blastocyst injection or embryo aggregation, giving rise to EC-embryo chimaeras. However, such chimaeras often develop abnormally. For example, diploid P19 cells colonize the embryo readily...
Journal Articles
Journal: Development
Development (1986) 95 (1): 95–115.
Published: 1 June 1986
... postimplantation mouse embryo chimaera microsurgery culture J. Embryol. exp. Morph. 95, 95-115 (1986) Printed in Great Britain © The Company of Biologists Limited 1986 95 Chimaerism of primordial germ cells in the early postimplantation mouse embryo following microsurgical grafting of posterior primitive...
Journal Articles
Journal: Development
Development (1986) 93 (1): 267–280.
Published: 1 April 1986
...Günter H. Schmidt; Maureen M. Wilkinson; Bruce A. J. Ponder The mosaicism in aortic endothelium of mouse aggregation chimaeras is demonstrated using the lectin Dolichos biflorus agglutinin as a strain-specific marker. The general fragmentary appearance and considerable size range of patches...
Journal Articles
Journal: Development
Development (1986) 91 (1): 197–208.
Published: 1 February 1986
...Günter H. Schmidt; Maureen M. Wilkinson; Bruce A. J. Ponder Clonal analysis of whole-mount preparations of entire retinal pigment epithelium (RPE), using SWR ↔ C57BL/6JLac and DDK ↔ C3H/Bi mouse aggregation chimaeras in which one of the two parental components predominated, revealed a markedly non...
Journal Articles
Journal: Development
Development (1985) 85 (1): 121–130.
Published: 1 February 1985
...Günter H. Schmidt; David J. Garbutt; Maureen M. Wilkinson; Bruce A. J. Ponder The epithelium of each individual intestinal crypt in adult mouse aggregation chimaeras is composed of cells of a single parental genotype (Ponder et al. 1985). Using a carbohydrate polymorphism recognized by Dolichos...