... transcriptional repressor is required in only one of three lineages that produce the same cell type. C. elegans FoxD3 Cell lineage Convergent differentiation Glia UNC-130 Hearst Foundations http://dx.doi.org/10.13039/100000933 National Human Genome Research Institute http...

... Natural Sciences and Engineering Research Council of Canada Universities Space Research Association Molecular specification of each cell lineage occurs during early development. The means by which these lineages diverge varies and it is of value to learn cell properties at the time cell fates...

...Kouhei Oonuma; Takehiro G. Kusakabe ABSTRACT The Ciona larva has served as a unique model for understanding the development of dopaminergic cells at single-cell resolution owing to the exceptionally small number of neurons in its brain and its fixed cell lineage during embryogenesis. A recent study...

... find that a single bifacial stem cell generates both xylem and phloem cell lineages. This cell is characterized by a specific combination of PXY ( TDR ), SMXL5 and WOX4 gene activity and a high division rate in comparison with tissue-specific progenitors. Our analysis provides a cellular fate map...

... http://www.biologists.com/user-licence-1-1/ Summary: Cell lineage analysis and live imaging reveals distinct region-specific cell behaviors in the visceral endoderm of mouse embryos during peri-implantation stages. Mouse embryogenesis Cell lineage Cell migration Visceral endoderm...

.... Zebrafish Fin regeneration Wound epidermis Cell lineage Fibronectin 1b Cre-loxP One of the important roles of the epidermis is to protect the internal homeostasis of multicellular organisms from external stresses, including mechanical and chemical damage, pathogens and radiation ( Chuong et al...

... it conversely increases these divisions in cortical progenitors. Although LGN inactivation increases the number of progenitors outside the ventricular zone in the developing neocortex, it has no effect on the position or number of progenitors in the retina. Retinal progenitor cell lineage analysis in LGN mutant...

... Taste bud precursor cell Fungiform taste papilla β-Catenin Sonic hedgehog (Shh) Glial-like taste cells Cell lineage Cre-lox Tamoxifen The sense of taste is mediated by multicellular taste buds in the oral cavity, which transmit chemical information via sensory nerves to the brain...

... mechanisms governing taste cell formation and turnover. Taste buds Gustatory system Sonic hedgehog Wnt/β-catenin Cell lineage Molecular genetics Taste dysfunction Dysgeusia Ageusia Chemotherapy Stem cells Lingual organoids Gustation, or the sense of taste, allows us to distinguish...

... bud renewal, specific steps in taste cell lineage progression are now identifiable via specific gene expression ( Miura and Barlow, 2010 ), including molecular markers for progenitors [K14, SOX2, GLI1, PTCH1 ( Okubo et al., 2009 )], precursors [SOX2, SHH, SKN-1A (POU2F3) ( Matsumoto et al., 2011...

... by fate map and time-lapse analyses . Dev. Biol. 233 , 365 - 379 . 10.1006/dbio.2001.0211 Kil S.-H. , Collazo A. ( 2002 ). A review of inner ear fate maps and cell lineage studies . J. Neurobiol. 53 , 129 - 142 . 10.1002/neu.10127 Kozlowski D. J. , Murakami T...

.... L. , Sandel M. J. , Waterston R. H. ( 2006 ). Automated cell lineage tracing in Caenorhabditis elegans . Proc. Natl. Acad. Sci. USA 103 , 2707 - 2712 . Bao Z. , Zhao Z. , Boyle T. J. , Murray J. I. , Waterston R. H. ( 2008 ). Control of cell cycle...

...Shunji Nakano; Ronald E. Ellis; H. Robert Horvitz Bilateral asymmetry in Caenorhabditis elegans arises in part from cell lineages that differ on the left and right sides of the animal. The unpaired MI neuron descends from the right side of an otherwise left-right symmetric cell lineage...

... ideas on how cell number and type must be regulated in building complete islets of Langerhans. * Author for correspondence( pedro.herrera@unige.ch ) 27 8 2009 © 2009. 2009 Cell lineage Clonal analysis Islet Mosaic Progenitor Transgenic Mouse How organs are assembled...

... beta-catenin-dependent switching events dictate cell-lineage determination. Cell 125 , 593 -605. Paredes, R. G. and Agmo, A. ( 2004 ). Has dopamine a physiological role in the control of sexual behavior? A critical review of the evidence. Prog. Neurobiol. 73 , 179 -226. Prakash, N...

... function directs cells towards the ICM in the preimplantation mouse embryo. J. Cell Sci. 118 , 505 -515. Price, J. and Thurlow, L. ( 1988 ). Cell lineage in the rat cerebral cortex: a study using retroviral-mediated gene transfer. Development 104 , 473 -482. Qian, X., Goderie, S. K., Shen, Q...

... into a single functional structure. * Author for correspondence (e-mail: daherzli@med.cornell.edu ) 8 3 2007 © 2007. 2007 Cell lineage Tailbud Urogenital system The urinary tract is composed of two distinct domains: the kidneys and a conduit system, which includes the ureters...

... that Notch signaling diversifies vertebrate neuron type by mediating similar binary fate decisions. Is binary fate specification a general mechanism for neuronal diversification in vertebrates? Recent cell lineage-tracing experiments show,for example, that neuronal progenitors can divide asymmetrically...

...Michiya Sugimori; Motoshi Nagao; Nicolas Bertrand; Carlos M. Parras; François Guillemot; Masato Nakafuku During development, the three major neural cell lineages, neurons,oligodendrocytes and astrocytes, differentiate in specific temporal orders at topologically defined positions. How the timing...

..., compartmental organization, proliferation and cell lineage of the PE in wing, second thoracic leg (T2) and eye discs. We show that a subset of peripodial cells in different imaginal discs undergo a cuboidal-to-squamous cell shape change at distinct larval stages. We find that this shape change requires both...