... transcriptional repressor is required in only one of three lineages that produce the same cell type. C. elegans FoxD3 Cell lineage Convergent differentiation Glia UNC-130 Hearst Foundations http://dx.doi.org/10.13039/100000933 National Human Genome Research Institute http...

... using scRNA-seq. Gene expression during lineage trajectories matches known gene regulatory network changes, and demonstrates both synchronous and asynchronous lineage resolutions. Sea urchin embryo scRNA-seq Gene regulatory networks Cell lineage National Institutes of Health http...

...Kouhei Oonuma; Takehiro G. Kusakabe ABSTRACT The Ciona larva has served as a unique model for understanding the development of dopaminergic cells at single-cell resolution owing to the exceptionally small number of neurons in its brain and its fixed cell lineage during embryogenesis. A recent study...

... find that a single bifacial stem cell generates both xylem and phloem cell lineages. This cell is characterized by a specific combination of PXY ( TDR ), SMXL5 and WOX4 gene activity and a high division rate in comparison with tissue-specific progenitors. Our analysis provides a cellular fate map...

.... and Nabeshima , Y.-I. ( 2003 ). Analysis of cell lineage in two- and four-cell mouse embryos . Development   130 , 5113 - 5122 . 10.1242/dev.00725 Gardner , R. L. and Cockroft , D. L. ( 1998 ). Complete dissipation of coherent clonal growth occurs before gastrulation in mouse epiblast...

.../ Summary: The fate of regenerative epidermis cells during zebrafish fin regeneration has been elucidated: they transiently contribute to the regenerated epidermis, but many are expelled by dynamic epidermal rearrangement. Zebrafish Fin regeneration Wound epidermis Cell lineage Fibronectin 1b...

... it conversely increases these divisions in cortical progenitors. Although LGN inactivation increases the number of progenitors outside the ventricular zone in the developing neocortex, it has no effect on the position or number of progenitors in the retina. Retinal progenitor cell lineage analysis in LGN mutant...

... bud precursor cell Fungiform taste papilla β-Catenin Sonic hedgehog (Shh) Glial-like taste cells Cell lineage Cre-lox Tamoxifen The sense of taste is mediated by multicellular taste buds in the oral cavity, which transmit chemical information via sensory nerves to the brain. In mammals...

... mechanisms governing taste cell formation and turnover. Taste buds Gustatory system Sonic hedgehog Wnt/β-catenin Cell lineage Molecular genetics Taste dysfunction Dysgeusia Ageusia Chemotherapy Stem cells Lingual organoids Gustation, or the sense of taste, allows us to distinguish...

... ‡ Authors for correspondence ( ophir.klein@ucsf.edu ; linda.barlow@ucdenver.edu ) Competing interests The authors declare no competing financial interests. 30 12 2013 27 5 2014 © 2014. Published by The Company of Biologists Ltd 2014 Cell lineage Mouse molecular genetics...

... ), i.e. examined otic primordia that had already initiated important morphogenetic changes. The resulting differences in methods and data sets have generated some unresolved questions, such as the possible existence of compartments or of cell lineage dispersion within the otic epithelium ( Bell et al...

.... J. , Waterston R. H. ( 2006 ). Automated cell lineage tracing in Caenorhabditis elegans . Proc. Natl. Acad. Sci. USA 103 , 2707 - 2712 . Bao Z. , Zhao Z. , Boyle T. J. , Murray J. I. , Waterston R. H. ( 2008 ). Control of cell cycle timing during C...

...Shunji Nakano; Ronald E. Ellis; H. Robert Horvitz Bilateral asymmetry in Caenorhabditis elegans arises in part from cell lineages that differ on the left and right sides of the animal. The unpaired MI neuron descends from the right side of an otherwise left-right symmetric cell lineage...

... , 1392 -1401. Delacour, A., Nepote, V., Trumpp, A. and Herrera, P. L. ( 2004 ). Nestin expression in pancreatic exocrine cell lineages. Mech. Dev. 121 , 3 -14. Deltour, L., Leduque, P., Paldi, A., Ripoche, M. A., Dubois, P. and Jami, J. ( 1991 ). Polyclonal origin of pancreatic islets...

...-mail: gil.levkowitz@weizmann.ac.il ) 26 8 2008 © 2008. 2008 Cell number Neuronal specification Oxytocin Dopamine Cell lineage Neural patterning cues, such as Wnt, provide progenitor cells with distinct positional identity and induce proneural proteins, which in turn initiate...

... progenitors Cell lineage Cell proliferation Pax6 Tbr2 (Eomes) The size of different brain regions depends on the size of the progenitor pool, which is in turn determined by the number of symmetric proliferative cell divisions. This concept, formulated by Rakic( Rakic, 1988 ), tries to explain...

... into a single functional structure. 8 3 2007 © 2007. 2007 Cell lineage Tailbud Urogenital system The urinary tract is composed of two distinct domains: the kidneys and a conduit system, which includes the ureters, bladder and urethra. The kidneys filter and modify blood in order...

... of the spinal cord (somite levels 6-15). † Author for correspondence (e-mail: b.appel@vanderbilt.edu ) * Present address: Graduate School of Medicine, Korea University, Ansan,South Korea 20 3 2007 © 2007. 2007 olig2 Neural precursors Motoneurons Interneurons Cell lineage...

...Michiya Sugimori; Motoshi Nagao; Nicolas Bertrand; Carlos M. Parras; François Guillemot; Masato Nakafuku During development, the three major neural cell lineages, neurons,oligodendrocytes and astrocytes, differentiate in specific temporal orders at topologically defined positions. How the timing...

..., compartmental organization, proliferation and cell lineage of the PE in wing, second thoracic leg (T2) and eye discs. We show that a subset of peripodial cells in different imaginal discs undergo a cuboidal-to-squamous cell shape change at distinct larval stages. We find that this shape change requires both...