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Keywords: ced-3
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Journal Articles
Journal: Development
Development (2007) 134 (7): 1357–1368.
Published: 1 April 2007
..., transcription of the egl-1 /BH3-only gene promotes cell-specific death. The EGL-1 protein inhibits the CED-9/Bcl-2 protein, resulting in the release of the caspase activator CED-4/Apaf-1. Subsequent activation of the CED-3 caspase by CED-4 leads to cell death. Despite the important role of egl-1 transcription...
Includes: Supplementary data