...Martin Klempt; Anne-Marie Hutchins; Peter D. Gluckman; Stephen J. M. Skinner ABSTRACT Binding proteins for the insulin-like growth factors (IGF-BPs) are important modulators of the biological actions of IGF-I and IGF-II. The generation of IGFBPs within developing organs, and their spatial...

...-like substance of non pituitary origin may influence fetal growth through the GH receptor. Accordingly, we have used immunohisto-chemisty, northern blot analysis, the reverse transcriptase-polymerase chain reaction and solution hybridization to study the ontogeny of the GH receptor/binding protein (BP...