... of the olfactory bulb and suggest that Kirrel-independent mechanisms contribute to axonal coalescence in the DI region. Kirrel2 Neph Kirrel3 Axonal guidance Sensory neurons Olfactory bulb The elaboration of precise neural maps in developing sensory systems allows organisms to obtain an accurate...

... to the ARP2/3 complex to regulate actin cytoskeleton remodeling. * Author for correspondence (e-mail: stringha@twu.ca ) 9 12 2008 © 2009. 2009 Cell migration Axonal guidance Cytoskeleton ARP2/3 complex C. elegans The successful development of multicellular organisms...

..., they are subject to a gonad-dependent attraction. The attractive cue is EGL-17/FGF, which mediates its effect via EGL-15/FGFR and a downstream signalling pathway that passes through the GRB2 adapter homologue SEM-5. Several other genes, which also function in axon guidance, are known to impinge on the sex myoblast...

... 2000 C. elegans Homeobox gene Axonal guidance Phox2 The development of the nervous system involves the navigation of axons towards their synaptic targets along complex and precise pathways. This navigation is directed by responses to repulsive and attractive cues ( Tessier-Lavigne...

...Dominique Bagnard; Marion Lohrum; Daniela Uziel; Andreas W. Püschel; Jürgen Bolz ABSTRACT Members of the semaphorin family have been implicated in mediating axonal guidance in the nervous system by their ability to collapse growth cones and to function as chemorepellents. The present findings show...

... with axons destined for the same nerve, suggesting that fasciculation may aid pathfinding. * Author for correspondence (e-mail: mhonig@utmen1.utmem.edu ) 17 02 1998 02 01 1997 © 1998 by Company of Biologists 1998 Pathfinding Neuronal specification Axonal guidance...

... of Glasgow, G11 6NU Scotland, UK 3 10 1997 © 1997 by Company of Biologists 1997 C. elegans mau-2 axonal guidance cell migration maternal effect As a guidance gene, mau-2 displays a number of novel properties. (1) It is the first pathfinding gene to be described...

.... Cell 82 , 1025-1036 (1995). The results of their analysis on the glide gene, which they called gcm ( glial cell missing ), are in agreement with ours. 06 10 1995 © 1996 by Company of Biologists 1996 cell fate gliogenesis axonal guidance Drosophila melanogaster...

... 1992 by Company of Biologists 1992 Brachydanio rerio axonal guidance identified vertebrate neurons single cell ablation The development of appropriate synaptic connections requires that neuronal growth cones navigate successfully to their correct target cells. Many different types...

... permissive fields and chemotropic cues is presented to account for our observations. * Author for correspondence 16 12 1991 © 1992 by Company of Biologists 1992 axonal guidance hindbrain facial nerve development The development of a functional nervous system depends upon...

... be important for proper development of the secondary motoneurons. Copyright © 1991 by Company of Biologists 1991 Brachydanio rerio axonal guidance cell commitment pathfinding Proper nervous system function requires that neurons make synaptic contacts with only the appropriate target...

... commissure. 10 10 1989 © 1990 by Company of Biologists 1990 axonal guidance pathfinding zebrafish neuronal differentiation The embryonic formation of axon tracts is the first step in the generation of the highly complex circuitry of the CNS. This process has been...

... would probably have formed in an abnormal orientation inside the rotated patch. We do not claim to have ruled out the possibility of axonal guidance by long-range attraction or by local directional or positional cues in the neuroepithelium. We have provided evidence for a third mechanism...

... of growing axons. 03 07 1989 © 1989 by Company of Biologists 1989 basal lamina axonal guidance axonal growth retina glial endfeet pigment epithelium chick embryo quail embryo A variety of investigations has shown that the initial outgrowth of axons is not random, but rather...

... be big for functional reasons, not because of limitations of accuracy of axonal guidance). In the environment of the target position, the guiding gradients are very shallow, the slope reducing to zero at the target position itself (see Figs 1 , 2 ). An accuracy of target identification of, say, 5...

... of proprioceptive fibres, which require guidance from motor axons over the final steps of their path into muscle. 14 02 1986 Copyright © 1986 by Company of Biologists 1986 limb innervation chick limb bud axonal guidance motoneurone sensory nerve growth cone The developing nerve...

... influenced by the axons which have preceded them. 03 07 1986 Copyright © 1985 by Company of Biologists 1985 retina optic tectum frog regeneration axonal guidance Xenopus laevis The retinotectal projection of fish and frogs differs from that of birds and mammals in that both...

... the rostral half of the somite. 24 09 1985 Copyright © 1985 by Company of Biologists 1985 neural crest somite axonal guidance fibronectin laminin. The cells of the neural crest are remarkable for the length and complexity of their migration pathway, and the number of cell types...