... , a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton . Development 122 , 1513 – 1522 . 10.1242/dev.122.5.1513 Bienz , M. and Müller , J. ( 1995 ). Transcriptional silencing of homeotic genes in Drosophila . BioEssays 17...

...’ activity proposed by Nieuwkoop in his ‘activation and transformation’ model for neural patterning. * Author for correspondence 18 09 1996 © 1996 by Company of Biologists 1996 fibroblast growth factor caudal cdx anteroposterior specification Hox genes Xenopus...

... anteroposterior specification Homeobox genes Pax-1 During axial skeleton development in vertebrates, each vertebra needs to acquire segment identity along the anteriorposterior (A-P) axis. Segment identity of the somitic mesoderm is conferred by spatially restricted distribution of Homeobox (Hox...

... by the organizer. This dorsalizing signal operates throughout gastrulation, can cross a Nuclepore membrane, and is not mimicked by lithium, FGFs or activin. Anteroposterior specification also takes place during gastrulation and is probably controlled by a dominant region at the posterior end of the forming axis...

... that there are two pseudoalleles. 26 11 1991 © 1992 by Company of Biologists 1992 Xenopus laevis Mesoderm induction dorsalization anteroposterior specification fibroblast growth factor induction In 1987 two groups found that basic fibroblast growth factor (bFGF/FGF-2) showed...

...J. M. W. Slack; D. Tannahill ABSTRACT Interest in the problem of anteroposterior specification has quickened because of our near understanding of the mechanism in Drosophila and because of the homology of Antennapedia-like homeobox gene expression patterns in Drosophila and vertebrates...