... sequence from the Joint Genome Institute (JGI) and the annotated protein ID 233300 for amphioxus Achaete-scute homolog gene product ( Satou et al., 2008 ), a pair of Achaete-scute homolog specific primers were designed, and Bam HI and Eco RI restriction enzyme sites were added to their 5′ ends...

...Michael J. Layden; Michiel Boekhout; Mark Q. Martindale achaete-scute homologs (ash) regulate neural development in all bilaterian model animals indicating that they represent a component of the ancestral neurogenic pathway. We test this by investigating four ash genes during development of a basal...

...Luc Vanolst; Catherine Fromental-Ramain; Philippe Ramain The GATA factor Pannier (Pnr) activates proneural expression through binding to a remote enhancer of the achaete-scute ( ac-sc )complex. Chip associates both with Pnr and with the (Ac-Sc)-Daughterless heterodimer bound to the ac-sc promoters...

... differentiation pathway, starting at the level of interstitial stem cells. Expression of Hyzic is restricted to the proliferative stages of nematoblasts. Hyzic acts before and possibly directly upstream of Cnash , a homolog of the proneural bHLH transcription factor gene achaete-scute , and of Nowa , an early...

...Scott R. Wheeler; Michelle L. Carrico; Beth A. Wilson; Susan J. Brown; James B. Skeath The study of achaete-scute ( ac/sc ) genes has recently become a paradigm to understand the evolution and development of the arthropod nervous system. We describe the identification and characterization of the ac...

.... Cell Dev. Biol. 16, 243-271). It specifies pattern in the dorsal body. On the dorsal notum it is expressed in a broad medial domain and directly regulates transcription of the achaete-scute ( ac-sc ) genes driving their expression in small discrete clusters within this domain at the sites of each...

...Daniela Pistillo; Nick Skaer; Pat Simpson In Drosophila the stereotyped arrangement of sensory bristles on the notum is determined by the tightly regulated control of transcription of the achaete-scute ( ac-sc ) genes which are expressed in small proneural clusters of cells at the sites of each...

...Corinna Wülbeck; Pat Simpson ABSTRACT The stereotyped positioning of sensory bristles in Drosophila has been shown to result from complex spatiotemporal regulation of the proneural achaete-scute genes, that relies on an array of cis- regulatory elements and spatially restricted transcriptional...

.... Thus, Wingless has only a permissive role on dorsocentral achaete-scute expression. We also provide evidence indicating that Pannier and U-shaped are main effectors of the regulation of wingless expression in the presumptive notum. * Author for correspondence (e-mail: jmodol@cbm.uam.es ) 02...

...Makoto Sato; Tetsuya Kojima; Tatsuo Michiue; Kaoru Saigo In Drosophila notum, the expression of achaete-scute proneural genes and bristle formation have been shown to be regulated by putative prepattern genes expressed longitudinally. Here, we show that two homeobox genes at the Bar locus ( BarH1...

...Carlos V. Cabrera; María C. Alonso; Hella Huikeshoven ABSTRACT The pattern of adult sensilla in Drosophila is established by the dosage-sensitive interaction of two antagonistic groups of genes. Sensilla development is promoted by members of the achaete - scute complex and the daughterless gene...

...Harald Vaessin; Michael Brand; Lily Yeh Jan; Yuh Nung Jan ABSTRACT The first steps of neuronal precursor formation require several genes that encode transcription regulators with the helix-loop-helix (HLH) motif, including the proneural genes of the achaete-scute complex AS-C ( achaete ( ac...

...Kathryn Zimmerman; John Shih; Julie Bars; Andres Collazo; David J. Anderson ABSTRACT We have isolated a novel Xenopus homolog of the Drosophila achaete-scute genes, called XASH-3. XASH-3 expression is neural specific and is detected as early as stage 11, making it one of the earliest markers...

...CARLOS V. CABRERA * We are sad to inform readers that Carlos Cabrera died on April 10th 1992 at the early age of 41. © 1992 by Company of Biologists 1992 Drosophila neurogenesis achaete-scute cell lineage cell interactions. REFERENCES Alonso M. C...