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Keywords: ZGA
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Journal Articles
Journal: Development
Development (2022) 149 (11): dev200854.
Published: 6 June 2022
...Yanna Dang; Shuang Li; Panpan Zhao; Lieying Xiao; Lefeng Wang; Yan Shi; Lei Luo; Shaohua Wang; Huanan Wang; Kun Zhang ABSTRACT The genome is transcriptionally inert at fertilization and must be activated through a remarkable developmental process called zygotic genome activation (ZGA). Epigenetic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev177402.
Published: 4 October 2019
... histones. Previous work suggests that the pool size of maternally provided histones can alter the timing of zygotic genome activation (ZGA) in frogs and fish. Here, we examine the effects of under- and overexpression of maternal histones in Drosophila embryogenesis. Decreasing histone concentration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev155366.
Published: 9 January 2018
... group of maternal transcripts after ZGA ( Giraldez et al., 2006 ). Zebrafish MZ dicer mutants, in which the whole microRNA processing pathway is inactive, show strong epiboly delay without affecting axis formation or other gastrulation movements ( Giraldez et al., 2005 ). Accumulation of non-degraded...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev147793.
Published: 9 January 2018
... genome activation ZGA Lineage tracing GESTALT The transcription factor Nanog is part of the core circuitry that regulates mammalian pluripotency (reviewed by Theunissen and Jaenisch, 2014 ). In vitro studies have shown that removal of Nanog triggers differentiation of mouse and human...
Includes: Supplementary data