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Keywords: Wound healing
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Journal Articles
Journal: Development
Development (2022) 149 (1): dev199587.
Published: 12 January 2022
... that colonic recovery from colitis-like injury depends on multiple Wnt-producing sources. Wntless Wnt Tagln Acta2 Gpr177 Colitis Wound healing Intestinal stem cell National Institutes of Health R01DK102934 R01DE026936 R01DE015654 R01DK119198 R01AT010243 American Cancer...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (1): dev181636.
Published: 2 January 2020
...Alan Y. Wong; Jessica L. Whited ABSTRACT Striking similarities between wound healing, epimorphic regeneration and the progression of solid tumors have been uncovered by recent studies. In this Review, we discuss systemic effects of tumorigenesis that are now being appreciated in epimorphic...
Journal Articles
Journal: Development
Development (2019) 146 (14): dev176693.
Published: 16 July 2019
... injury. This observation hints towards a role for the Eda pathway in controlling the switch from basal to reflex tears, to support corneal wound healing. Collectively, our data suggest a crucial implication of Eda signaling in the cornea–lacrimal gland feedback loop, both in physiological...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev176974.
Published: 8 May 2019
... advances in wound healing, repair and regeneration. The meeting covered a wide range of regeneration models and tissues, identification of regulatory genes and signals, and striking advances toward regenerative therapies. Here, we report some of the exciting topics discussed during this conference...
Journal Articles
Journal: Development
Development (2019) 146 (4): dev169037.
Published: 15 February 2019
... taken place. Further genetic analysis revealed that the activation of the initiator caspase Dronc is coupled with the generation of reactive oxygen species. The activation of Dronc also regulates myosin levels and delays wound healing. Our findings suggest a possible function for non-apoptotic caspase...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev159905.
Published: 8 January 2018
... (Corning) using MEF-conditioned hPSC medium (GlobalStem) and handled as previously described ( James et al., 2006 ). All cell lines were confirmed to be mycoplasma free every ten passages. Many groups have linked inhibition of Wnt signaling to improved wound healing following MI. Transgenic mice...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (3): 357–364.
Published: 1 February 2017
... and highlights the diversity of regeneration strategies in different organ systems and species. Cell plasticity and cell reprogramming Blastema dynamics Model systems Immune response Transcriptional control of regeneration Wound healing Injury-induced signaling Senescence and ageing Since...
Journal Articles
Journal: Development
Development (2016) 143 (19): 3491–3505.
Published: 1 October 2016
... ). The cell cycle during amphibian limb regeneration . J. Cell Sci.   20 , 539 - 547 . Witschi , H. ( 1968 ). Inhibition of deoxyribonucleic acid synthesis in regenerating rat liver by beryllium . Lab. Invest.   19 , 67 - 70 . Beryllium Regeneration Wound healing Limb development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (12): 2077–2088.
Published: 15 June 2016
... cellular processes that take place both within the epidermis and in other participating tissues. Re-epithelialization of partial- or full-thickness skin wounds of adult zebrafish, however, is extremely rapid and largely independent of the other processes of wound healing. Live imaging after treatment...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (12): 2160–2171.
Published: 15 June 2016
... signaling and cell proliferation to maintain normal epithelial thickness. Primary cilia Cornea Ocular surface Notch signaling Epithelium Wound healing Mouse The outermost layer of the cornea consists of a stratified non-keratinized pseudosquamous epithelium known as corneal epithelium...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (11): 1960–1970.
Published: 1 June 2015
... is essential for: (1) general mRNA translation during embryogenesis, (2) developmental re-programming upon manipulations to the embryo and (3) larval wound healing. We also learned that Vasa interacted with mRNAs in the perinuclear area and at the spindle in an Importin-dependent manner during cell cycle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (14): 2901–2911.
Published: 15 July 2014
... Epithelial morphogenesis Junctional dynamics Mechanical forces Quantitative image analysis Segmentation algorithms Wound healing Drosophila Epithelial tissues display an ability to repair wounds. This ability is remarkable in embryos, in which epidermal wounds heal rapidly, with little...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (9): 1814–1820.
Published: 1 May 2014
... and epidermal movement in embryonic wound-healing . Nature 360 , 179 - 183 . 10.1038/360179a0 Martin P. , Parkhurst S. M. ( 2004 ). Parallels between tissue repair and embryo morphogenesis . Development 131 , 3021 - 3034 . 10.1242/dev.01253 Martin A. C. , Kaschube M...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (7): 1517–1527.
Published: 1 April 2013
...Barbara A. Schmidt; Valerie Horsley Acute wound healing in the skin involves the communication of multiple cell types to coordinate keratinocyte and fibroblast proliferation and migration for epidermal and dermal repair. Many studies have focused on the interplay between hematopoietic cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (22): 4843–4852.
Published: 15 November 2011
... into the wound epithelium or into the growing HF, respectively ( Ito et al., 2005 ). Fig. 2. Lhx2 expression increases in hair follicles during wound healing. qRT-PCR for Lhx2 was performed with RNA from mouse skin wounds at different days after wounding. Cryosections of the wounded human and mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (20): 3505–3514.
Published: 15 October 2009
...,and inhibition of cell motility and in vitro wound healing. Although the rate of cell proliferation was reduced, terminal differentiation was unaffected. To assess the role of Necl2 in vivo, we examined the epidermis of Necl2 -null mice and developed transgenic mice that expressed Necl2 in the basal layer...
Journal Articles
Journal: Development
Development (2009) 136 (15): 2557–2565.
Published: 1 August 2009
... hemocyte chemotaxis during development and wound healing in Drosophila melanogaster. J. Cell Biol. 173 , 405 -416. Yamakita, Y., Ono, S., Matsumura, F. and Yamashiro, S. ( 1996 ). Phosphorylation of human fascin inhibits its actin binding and bundling activities. J. Biol. Chem. 271 , 12632 -12638...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (7): 1279–1289.
Published: 1 April 2007
... in a subset of NC cells that form craniofacial cartilage. Cells lacking Inca migrate successfully but fail to condense into skeletal primordia. Overexpression of Inca disrupts cortical actin and prevents formation of actin `purse strings', which are required for wound healing in Xenopus embryos. We show...
Journal Articles
Journal: Development
Development (1985) 85 (1): 95–109.
Published: 1 February 1985
...Leslie Dale; Mary Bownes When complementary fragments of the imaginal wing disc of Drosophila are cultured for several days prior to inducing metamorphosis, usually one fragment will regenerate while the second duplicates. It has been proposed that wound healing plays an important part in disc...