..., hippocampus development is known to be regulated by the hem organizer. Here, we have identified that, in birds, Wnt7b secreted from the hem is sufficient for inducing the expression of hippocampal markers. Furthermore, we have demonstrated that a microRNA, miR-19b, which is selectively excluded from the hem...

... of kidney organization and function is regulated by Wnt7b signaling. The future collecting duct network specifically expresses Wnt7b . In the absence of Wnt7b , cortical epithelial development is normal but the medullary zone fails to form and urine fails to be concentrated normally. The analysis of cell...

...Weiguo Shu; Yue Qin Jiang; Min Min Lu; Edward E. Morrisey Although the Wnt signaling pathway regulates inductive interactions between epithelial and mesenchymal cells, little is known of the role that this pathway plays during lung development. Wnt7b is expressed in the airway epithelium...