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Keywords: Wnt1
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Journal Articles
Journal: Development
Development (2013) 140 (6): 1342–1352.
Published: 15 March 2013
...Jasmine Yang; Ashly Brown; Debra Ellisor; Erin Paul; Nellwyn Hagan; Mark Zervas Wnt1 -expressing progenitors generate midbrain dopamine (MbDA) and cerebellum (Cb) neurons in distinct temporal windows and from spatially discrete progenitor domains. It has been shown that Wnt1 and Lmx1a participate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (9): 1662–1669.
Published: 1 May 2012
... of Wnt1, the posterior-ventral region of the embryo is severely altered during early gastrulation. Strikingly, at this time, nodal and its downstream target genes gsc and bra are expressed ectopically, extending posteriorly to the blastopore. They override the initial specification of posterior-ventral...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (10): 1717–1726.
Published: 15 May 2009
... of neurons does not seem to result from a defect in NCC specification as all the usual markers, with the exception of Msx1 , are expressed in the dorsal caudal-most NT as early as E4/HH24. However, Bmp4-Wnt1 signaling, which triggers trunk NCC delamination, is impaired in this region due to persistence...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2008) 135 (3): 441–450.
Published: 1 February 2008
...Alfonso Lavado; Oleg V. Lagutin; Guillermo Oliver The homeobox gene Six3 represses Wnt1 transcription. It is also required in the anterior neural plate for the development of the mammalian rostral forebrain. We have now determined that at the 15- to 17-somite stage, the prospective diencephalon...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (18): 3339–3348.
Published: 15 September 2007
...Lisa M. Galli; Tiffany L. Barnes; Stephanie S. Secrest; Tatsuhiko Kadowaki; Laura W. Burrus A long-term goal of developmental biology is to understand how morphogens establish gradients that promote proper tissue patterning. A number of reports describe the formation of the Wg (Wnt1) gradient...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (22): 5319–5330.
Published: 15 November 2003
... domain upon which the cerebellum fuses. Elimination or overgrowth of this isthmic domain in Wnt1 sw/sw and En1 +/Otx2lacZ mutant mice, respectively, impair cerebellar midline fusion. Because the isthmus-derived midline cerebellar domain displays a distinct expression pattern of genes involved in BMP...
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (22): 5269–5277.
Published: 15 November 2002
...Eiji Matsunaga; Tatsuya Katahira; Harukazu Nakamura The isthmus is the organizing center for the tectum and cerebellum. Fgf8 and Wnt1 are secreted molecules expressed around the isthmus. The function of Fgf8 has been well analyzed, and now accepted as the most important organizing signal...
Journal Articles
Journal: Development
Development (2002) 129 (20): 4763–4772.
Published: 15 October 2002
...Isabel Olivera-Martinez; Sylvain Missier; Sandrine Fraboulet; Jacques Thélu; Danielle Dhouailly The chick dorsal feather-forming dermis originates from the dorsomedial somite and its formation depends primarily on Wnt1 from the dorsal neural tube. We investigate further the origin...
Journal Articles
Journal: Development
Development (2001) 128 (24): 4979–4991.
Published: 15 December 2001
... -229. Hidalgo-Sanchez, M., Millet, S., Simeone, A. and Alvarado-Mallart, R. M. ( 1999 a). Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain. Mech. Dev . 81 , 175 -178. Hidalgo-Sanchez, M., Simeone...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (19): 3665–3674.
Published: 1 October 2001
... Xenopus Frizzled Wnt Wnt1 Frizzled 3 Neural crest PDZ domain Dishevelled GIPC Wnt1 was first identified as an oncogene activated by provirus insertion ( Nusse and Varmus, 1992 ). Subsequently, Wnt1 was shown to be a member of a family of secreted glycoproteins (Wnts) that regulate cell...
Journal Articles
Journal Articles
Journal: Development
Development (2001) 128 (2): 181–191.
Published: 15 January 2001
..., we found that Fgf8, Wnt1 and Pax5 do not require the En genes for initiation of expression, but do for their maintenance, and Pax6 expression is expanded caudally into the midbrain in the absence of EN function. Since E9.5 En1/2 double mutants lack the mid/hindbrain region, forebrain mutant explants...
Journal Articles
Journal: Development
Development (2000) 127 (9): 1857–1867.
Published: 1 May 2000
..., maintains the expression of the secreted factor Wnt1. Our conclusions are substantiated by the following: (i) Lmx1b mRNA becomes localized to the isthmus immediately after Fgf8 initiation, (ii) Wnt1 expression is localized to the Lmx1b expression domain, but with slightly later kinetics, (iii) Fgf8 -soaked...
Journal Articles
Journal: Development
Development (2000) 127 (2): 319–331.
Published: 15 January 2000
... to regulation at the level of mRNA translation or protein stability. In the embryonic neuroepithelium, Myf5 is transcribed in differentiated neurons after the expression of neural basic Helix-Loop-Helix transcription factors. The signalling molecules Wnt1 and Sonic hedgehog, implicated in the activation of Myf5...
Journal Articles