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Keywords: Wnt agonistClose
In collection:Musculoskeletal system
Shihai Jia, Jing Zhou, Christopher Fanelli, Yinshen Wee, John Bonds, Pascal Schneider, Gabriele Mues, Rena N. D'Souza
Development (2017) 144 (20): 3819–3828.
Published: 15 October 2017
... surgically and require complex life-long treatments. Our studies utilized the well-characterized Pax9 −/− mouse model with a consistent cleft palate phenotype to test small-molecule Wnt agonist therapies. We show that the absence of Pax9 alters the expression of Wnt pathway genes including Dkk1 and Dkk2...
Includes: Supplementary data