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Keywords: Vulva
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Journal Articles
Journal: Development
Development (2021) 148 (5): dev194167.
Published: 5 March 2021
... for the development of the vulva by promoting the localization of the sole Epidermal growth factor receptor (EGFR) ortholog LET-23 to the basolateral membrane of the vulva precursor cells where it can specify the vulval cell fate. To understand how the LIN-2/7/10 complex regulates receptor localization, we determined...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (21): 4649–4660.
Published: 1 November 2011
... metazoan development, but their role in controlling organ morphogenesis is less understood. Here, we show that the C. elegans hox gene lin-39 regulates epidermal morphogenesis via its novel target, the essential zinc finger protein VAB-23. During the development of the vulva, the egg-laying organ...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (22): 4053–4062.
Published: 15 November 2007
.... These results demonstrate how ROR proteins help to refine the spatial pattern of Wnt activity in a complex multicellular environment. * Author for correspondence (e-mail: pws@caltech.edu ) 25 8 2007 © 2007. 2007 ROR CAM-1 Wnt Vulva Patterning CRD Organogenesis Morphogen...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (17): 3461–3471.
Published: 1 September 2006
.... † Author for correspondence (e-mail: ahajnal@zool.unizh.ch ) * These authors contributed equally to this work 15 6 2006 © 2006. 2006 Caenorhabditis elegans Vulva Pumilio Translational control Signal transduction The spatial and temporal regulation of gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (4): 755–765.
Published: 15 February 2004
... address: UCMP, Umea University, SE-901 87 Umea, Sweden 4 11 2003 © 2004. 2004 PP2A PR55 Raf PAR-1 Vulva C. elegans The kinase Raf is a key target of the Ras GTPase during both normal development and oncogenesis, and acts upstream of MEK and ERK in the mitogen activated...
Journal Articles
Journal: Development
Development (2003) 130 (19): 4553–4566.
Published: 1 October 2003
... that involves activation of the heterotrimeric Gαq protein, EGL-30. EGL-30 acts with muscle-expressed EGL-19 L-type voltage-gated calcium channels to promote vulva development, and acts downstream or parallel to LET-60 (RAS). This pathway is not essential for vulval induction on standard Petri plates,but can...
Journal Articles
Journal: Development
Development (2003) 130 (12): 2589–2601.
Published: 15 June 2003
... development ( Baird et al.,1991 ; Chow and Emmons,1994 ). † Author for correspondence (e-mail: pws@caltech.edu ) 17 3 2003 © 2003. 2003 C. elegans lin-11 ldb-1 LIM homeodomain Vulva Differentiation Specification of different cell types during development...
Journal Articles
Journal: Development
Development (2003) 130 (1): 57–69.
Published: 1 January 2003
...-transfer in C. elegans. Nucleic Acids Res. 22 , 1762 -1763. Greenwald, I. ( 1997 ). Development of the vulva. In C. Elegans II (ed. D. L. Riddle, T. Blumenthal, B. J. Meyer and J. R. Priess), pp. 519 -541. Cold Spring Harbor, NY: Cold Spring Habor Laboratory Press. Gustafsson, C. M...
Journal Articles
Journal: Development
Development (2002) 129 (22): 5171–5180.
Published: 15 November 2002
...Kyunghee Koh; Sara M. Peyrot; Cricket G. Wood; Javier A. Wagmaister; Morris F. Maduro; David M. Eisenmann; Joel H. Rothman Development of the vulva in C. elegans is mediated by the combinatorial action of several convergent regulatory inputs, three of which,the Ras, Wnt and Rb-related pathways, act...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3395–3404.
Published: 15 September 2001
...Benno Jungblut; André Pires-daSilva; Ralf J. Sommer The invariant cell lineage of nematodes allows the formation of organ systems, like the egg-laying system, to be studied at a single cell level. The Caenorhabditis elegans egg-laying system is made up of the vulva, the mesodermal gonad...
Journal Articles
Journal: Development
Development (1993) 119 (Supplement): 9–18.
Published: 1 December 1993
...Russell J. Hill; Paul W. Sternberg Precursor cells of the vulva of the C. elegans hermaphrodite choose between two vulval cell fates (1° and 2°) and a non-vulval epidermal fate (3°) in response to three intercellular signals. An inductive signal produced by the anchor cell induces the vulval...