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Keywords: Ubiquitylation
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Journal Articles
Journal: Development
Development (2023) 150 (10): dev200848.
Published: 22 May 2023
... by monoubiquitylating DLX3. Our findings suggest that the two E3 ubiquitin ligases CHIP and MDM2 reciprocally regulate DLX3 activity by catalyzing distinct types of ubiquitylation, and reveal an important mechanism by which differentiation of odontoblasts is delicately regulated by divergent post-translational...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (14): dev199461.
Published: 16 July 2021
... by the late two-cell stage and then transported to lysosomes for degradation at the later stages. During this process, large amounts of ubiquitylated proteins accumulated on endosomes. Furthermore, the degradation of GlyT1a with mutations in potential ubiquitylation sites was delayed, suggesting...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (24): dev169797.
Published: 13 December 2018
... interaction between p53 and the zinc-dependent E3 ubiquitin ligase Mdm2, and greatly reduced p53 ubiquitylation. Overexpression of human CHIP, a zinc-independent E3 ubiquitin ligase that targets p53, relieved TPEN-induced p53 stabilization and reduced apoptosis. Expression of p53 pro-apoptotic target genes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev165340.
Published: 3 September 2018
... cord RNF220 ZC4H2 p2 domain V2 interneuron Ubiquitylation Mouse Chick In the developing ventral spinal cord, progenitor cell populations in each specific progenitor domain give rise to a distinct type of neuron, which eventually contributes to motor circuits ( Goulding and Lamar, 2000...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 2984–2992.
Published: 1 August 2014
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Axis formation Par-1 SCF Ubiquitylation Apical-basal polarity Oskar Since the hs-Slmb-rescued slmb transheterozygotes show a weaker phenotype in the germline than slmb...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (19): 3600–3612.
Published: 1 October 2012
... 2012. Cdh1-APC Smurf1 Axon growth Myelin Ubiquitylation Mouse Rat Axon growth is a crucial process in the developing nervous system. It is controlled by a large number of extrinsic regulatory events, which trigger signaling cascades that involve small GTPase-controlled...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (18): 3057–3065.
Published: 15 September 2009
...-houston@uiowa.edu ) 23 7 2009 © 2009. © 2009. 2009 Xenopus Dorsal axis Wnt Microtubules Cortical rotation Trim Ubiquitylation Understanding the establishment of the embryonic body axis from a symmetrical egg has been a long-standing problem in developmental biology...
Includes: Multimedia, Supplementary data