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Keywords: Trithorax
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Journal Articles
Journal: Development
Development (2019) 146 (23): dev183400.
Published: 2 December 2019
... Polycomb Trithorax During development of the central nervous system (CNS), neural stem cells (NSCs) divide asymmetrically to generate daughter cells with self-renewing capacity but also complex neurogenic and gliogenic lineages. Regulation of this process requires tight and highly dynamic control...
Includes: Supplementary data
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Journal Articles
Journal Articles
Journal: Development
Development (2013) 140 (16): 3478–3485.
Published: 15 August 2013
... classifies Utx as a trithorax group regulator. We propose that Utx is needed in the early embryo to prevent inappropriate instalment of long-term Polycomb repression at HOX genes in cells in which these genes must be kept active. In contrast to PRC2, which is essential for, and continuously required during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (11): 1929–1938.
Published: 1 June 2009
...Ming Fang; Hongyan Ren; Jiabin Liu; Ken M. Cadigan; Sanjeevkumar R. Patel; Gregory R. Dressler Development of the fruit fly Drosophila depends in part on epigenetic regulation carried out by the concerted actions of the Polycomb and Trithorax group of proteins, many of which are associated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (14): 2383–2390.
Published: 15 July 2008
...Svetlana Petruk; Sheryl T. Smith; Yurii Sedkov; Alexander Mazo Polycomb group (PcG) and trithorax group (trxG) proteins act in an epigenetic fashion to maintain active and repressive states of expression of the Hox and other target genes by altering their chromatin structure. Genetically, mutations...
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (4): 667–678.
Published: 15 February 1998
... trithorax trithoraxgleich zinc finger homeodomain protein-1 Mesoderm Cell migration Cellular movements play a crucial role in the development of a multicellular organism. They can serve a variety of functions ranging from creating different tissue layers during gastrulation to the processes...
Journal Articles
Journal: Development
Development (1996) 122 (12): 4073–4083.
Published: 1 December 1996
... distribution of E(Z) protein and discuss their implications concerning putative functional domains. Finally, we describe the effect a trithorax mutation has on E(Z) chromosome binding. * Author for correspondence (e-mail: rjones@mail.smu.edu ) 22 08 1996 © 1996 by Company of Biologists 1996...
Journal Articles
Journal: Development
Development (1995) 121 (6): 1649–1656.
Published: 1 June 1995
... wing surfaces. This effect is one of the somatic clone phenotypes of trithorax ( trx ) lethals. A similar dorsal-to-ventral transformation is observed in Pc Dlw/Dlw clones. Dlw 1 /Dlw 1 clones have no effect elsewhere, except in the dorsal notum, which may differentiate extra macrochaetes. We propose...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1985) 89 (1): 349–365.
Published: 1 October 1985
...P. W. Ingham ABSTRACT The requirement for the trithorax gene during imaginal cell proliferation has been analysed by clonal analysis. Clones carrying the allelic Regulator of bithorax and trithorax mutations were induced by mitotic recombination at different developmental stages. The results...