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Keywords: Transposon
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Journal Articles
Journal: Development
Development (2022) 149 (16): dev200692.
Published: 22 August 2022
...Zoran Gajic; Diljeet Kaur; Julie Ni; Zhaorong Zhu; Anna Zhebrun; Maria Gajic; Matthew Kim; Julia Hong; Monika Priyadarshini; Christian Frøkjær-Jensen; Sam Gu ABSTRACT Despite the prominent role of endo-siRNAs in transposon silencing, their expression is not limited to these ‘nonself’ DNA elements...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (12): dev190793.
Published: 25 June 2021
... the essential role of eIF4E in the transition from maternal to embryonic control of mouse development. Cap-dependent translation Early embryo development Mammalian maternal embryonic transition Transposon Mouse Reproduction in all metazoans requires the conversion of the terminally...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2019) 146 (12): dev171157.
Published: 1 February 2019
... ). Developmentally regulated piRNA clusters implicate MILI in transposon control . Science   316 , 744 - 747 . 10.1126/science.1142612 Aravin , A. A. , Sachidanandam , R. , Bourc'his , D. , Schaefer , C. , Pezic , D. , Toth , K. F. , Bestor , T. and Hannon , G. J. ( 2008...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (20): dev167346.
Published: 22 October 2018
... reveals tight coupling with germline development and a striking nuclear enrichment of these transcripts. Epigenetic inheritance Histone methyltransferase Nuclear RNA localization Nuclear RNAi smFISH Transposon Besides the classical RNA interference (RNAi) pathway, in which a target gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev161190.
Published: 28 August 2018
... of I element peptides forming aggregates in the nuclei of rescued P180-depleted nurse cells but never in control nurse cells ( Fig. 5 A-D). As p53 has been shown to restrain the expression of transposons ( Wylie et al., 2016 ), there may be a cumulative effect on the expression of I element peptides...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (16): 2925–2939.
Published: 15 August 2017
... induction of Class I retrotransposons and activation of cytoplasmic DNA viral sensors. Attenuating Sting, phosphorylated Tbk1 and, importantly, blocking reverse transcriptase activity suppressed the expression of interferon genes in uhrf1 mutants. Thus, activation of transposons in cells with global DNA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (3): 530–539.
Published: 1 February 2016
... proteins silence transposons in a manner that is strictly dependent on their sequence complementarity. Hence, a key goal in understanding piRNA pathways is to determine mechanisms that modulate piRNA sequences. Here, we identify a protein-protein interaction between the 3′-to-5′ exoribonuclease Nibbler...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (18): 4039–4050.
Published: 15 September 2011
... transposon regulation in both germline and somatic gonadal tissues. We show that Vret, which contains Tudor domains, associates physically with Piwi and Aubergine (Aub), stabilizing these proteins via a gonad-specific mechanism that is absent in other fly tissues. In the absence of vret , Piwi-bound piRNAs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (20): 4085–4096.
Published: 15 October 2006
...Koji Tanabe; Yoshiko Takahashi; Yuki Sato; Koichi Kawakami; Masatoshi Takeichi; Shinichi Nakagawa Dendrite morphology of neurons provides a structural basis for their physiological characteristics, and is precisely regulated in a cell type-dependent manner. Using a unique transposon-mediated gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (10): 2401–2409.
Published: 15 May 2002
... of a mutant, atk1-1, which has a defective ATK1 gene. The atk1-1 mutant was identified in a collection of Ds transposon insertion lines by its reduced fertility. Reciprocal crosses between the atk1-1 mutant and wild type showed that only male fertility was reduced, not female fertility. Molecular analyses...