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Keywords: Transplantation
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Journal Articles
Journal: Development
Development (2022) 149 (8): dev200139.
Published: 24 January 2022
... reduced the number of B1a cells, MZBs, ILC2s and Tregs, both in situ and upon transplantation, indicating an intrinsic and essential role for IL7Rα. Surprisingly, reciprocal transplants of wild-type HSCs showed that an IL7Rα −/− environment selectively impaired reconstitution of TLCs when compared...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1375–1386.
Published: 1 April 2015
... demonstrated by the induction of the striatal transcription factors CTIP2, GSX2 and FOXP2. Crucially, these human LGE progenitors readily differentiate into postmitotic neurons expressing the striatal projection neuron signature marker DARPP32, both in culture and following transplantation in the adult...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (9): 1443–1452.
Published: 1 May 2009
... month,some cells express MBP. ( K ) Three months after transplantation, the grafted cells, as revealed by hNA and MBP, preferentially localize in the corpus callosum (CC, outlined). ( L ) All of the human cells are positive for OLIG2. ( M ) The human cells exhibit multiple MBP + processes. ( N...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (10): 1853–1859.
Published: 15 May 2007
... and generated offspring following spermatogonial transplantation into the testes of infertile recipient mice, indicating that they are functionally normal. These results demonstrate that activation of the PI3K-Akt pathway plays a central role in the self-renewal division of spermatogonial stem cells. Studies...
Journal Articles
Journal: Development
Development (2007) 134 (3): 449–454.
Published: 1 February 2007
... is sufficient to induce a fully functional testicular soma capable of supporting complete spermatogenesis in the XX body. Here, we demonstrate that the testicular somatic environment of XX/Sry males is defective in supporting the later phases of spermatogenesis. Spermatogonial transplantation analyses using XX...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (18): 3671–3681.
Published: 15 September 2006
... a single progenitor to theoretically form sufficient cells for∼4×10 7 adult brains. AHNPs longitudinally maintain the ability to generate both glial and neuronal cell types in vivo and in vitro,and are amenable to genetic modification and transplantation. These findings suggest an unprecedented degree...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (1): 117–122.
Published: 1 January 2005
..., and the maturation process, from epiblast cells through PGCs to postnatal spermatogonia, can occur in the postnatal testicular environment. Primordial germ cell transplantation techniques will also provide a novel tool to assess the developmental potential of PGCs, such as those manipulated in vitro or recovered...
Journal Articles
Journal: Development
Development (2004) 131 (14): 3367–3379.
Published: 15 July 2004
.... We used two cell labels, wheat germ agglutinin gold conjugates(WGA-Au) ( Smits-van Prooije et al.,1986 ; Chan and Tam,1988 ; Trainor and Tam,1995 ) and DiI, to label the premigratory neural crest by direct microinjection or by orthotopic transplantation of a fragment of labelled neural crest tissue...
Journal Articles
Journal: Development
Development (2004) 131 (2): 479–487.
Published: 15 January 2004
... BCRP1/ABCG2 Transplantation Spermatogenesis is a step-wise process that requires coordination of mitosis, meiosis and differentiation. Numerous knockout and spontaneously mutated murine models exhibit altered spermatogenesis, underscoring the complexity of homeostatic control in this lineage...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4955–4962.
Published: 15 October 2003
...Anne Holz; Barbara Bossinger; Thomas Strasser; Wilfried Janning; Robert Klapper As in many other organisms, the blood of Drosophila consists of several types of hemocytes, which originate from the mesoderm. By lineage analyses of transplanted cells, we specified two separate anlagen that give rise...
Journal Articles
Journal: Development
Development (2002) 129 (2): 433–442.
Published: 15 January 2002
... -1349. Sadaghiani, B. and Theibaud, C. H. ( 1987 ). Neural crest development in the Xenopus laevis embryo, studies by interspecific transplantation and scanning electron microscopy. Dev. Biol . 124 , 91 -110. Saldivar, J., Krull, C., Krumlauf, R., Ariza-McNaughton, L. and Bronner-Fraser...
Journal Articles
Journal: Development
Development (2001) 128 (13): 2517–2524.
Published: 1 July 2001
...Robert Klapper; Sandra Heuser; Thomas Strasser; Wilfried Janning In order to reveal syncytia within the visceral musculature of Drosophila melanogaster , we have combined the GAL4/UAS system with the single-cell transplantation technique. After transplantation of single cells from UAS-GFP donor...
Journal Articles
Journal: Development
Development (1986) 97 (Supplement): 181–196.
Published: 1 October 1986
... be localized. The localization may be exclusive or merely quantitative. Second, it must be shown that the localized components are necessary and/or sufficient for cell determination. Copyright © 1986 by Company of Biologists 1986 Chironomus microinjection egg determinants anterior transplantation...
Journal Articles
Journal: Development
Development (1985) 88 (1): 281–291.
Published: 1 August 1985
...R. S. P. Beddington This paper describes a technique for transplanting early postimplantation mouse embryos from their own implantation site to a decidua in another pregnant mouse. Evidence is provided that this procedure is compatible with their continued development. At a low frequency both 6th...