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Journal Articles
Journal: Development
Development (2023) 150 (2): dev201563.
Published: 24 January 2023
... Spearman correlation ( Fig. S3 ). This analysis also revealed strong correlation between Psi and RNA Polymerase-binding profiles (ranging from 0.53 to 0.8), further suggesting Psi binding overlaps transcriptionally active regions of the genome. Reassuringly, significant enrichment (normalised log 2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (23): dev201124.
Published: 30 November 2022
...Gianluca Zambanini; Anna Nordin; Mattias Jonasson; Pierfrancesco Pagella; Claudio Cantù ABSTRACT Upon WNT/β-catenin pathway activation, stabilized β-catenin travels to the nucleus where it associates with the TCF/LEF transcription factors, constitutively bound to genomic Wnt-responsive elements...
Includes: Supplementary data
Journal Articles
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Reproductive biology
Journal: Development
Development (2022) 149 (21): dev200819.
Published: 3 November 2022
... Ganesh , S. , Horvat , F. , Drutovic , D. , Efenberkova , M. , Pinkas , D. , Jindrova , A. , Pasulka , J. , Iyyappan , R. , Malik , R. , Susor , A. et al. ( 2020 ). The most abundant maternal lncRNA Sirena1 acts post-transcriptionally and impacts mitochondrial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (16): dev200398.
Published: 30 August 2022
... promoter structures, G-quadruplexes and transcriptionally active enhancers . Nucleic Acids Res. 46 , 7566 - 7585 . 10.1093/nar/gky554 Lai , F. , Orom , U. A. , Cesaroni , M. , Beringer , M. , Taatjes , D. J. , Blobel , G. A. and Shiekhattar , R. ( 2013...
Journal Articles
Journal: Development
Development (2022) 149 (11): dev200153.
Published: 6 June 2022
...Cai-Li Bi; Qian Cheng; Ling-Yue Yan; Hong-Yan Wu; Qiang Wang; Ping Wang; Lin Cheng; Rui Wang; Lin Yang; Jian Li; Feng Tie; Hao Xie; Ming Fang ABSTRACT The evolutionarily conserved C-terminal binding protein (CtBP) has been well characterized as a transcriptional co-repressor. Herein, we report...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (3): dev200074.
Published: 9 February 2022
... of Biologists Ltd 2022 We previously identified an essential function of TBP-associated factor 4b (TAF4b) in the establishment of the ovarian reserve in the embryonic mouse ovary ( Grive et al., 2014 , 2016 ). TAF4b is a germ cell-enriched subunit of the transcription factor TFIID complex, which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (24): dev199991.
Published: 17 December 2021
... alleles are transcriptionally active. The median fluorescence intensity of twi TSs along the DV axis was also uniform, indicating a similar rate of Pol II loading onto all twi loci throughout the mesodermal domain ( Fig. 2 D). The uniform activation of twi transcription is also corroborated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev199744.
Published: 7 September 2021
... in transcription-dependent condensates . Science 361 , 412 - 415 . 10.1126/science.aar4199 Cisse , I. I. , Izeddin , I. , Causse , S. Z. , Boudarene , L. , Senecal , A. , Muresan , L. , Dugast-Darzacq , C. , Hajj , B. , Dahan , M. and Darzacq , X. ( 2013...
Journal Articles
Journal: Development
Development (2021) 148 (17): dev199477.
Published: 6 September 2021
... maternal and zygotic Stat3 expression display transient axis elongation defects due to reduced cell proliferation during embryogenesis ( Liu et al., 2017 ). In addition, it has been recently demonstrated in zebrafish that Stat3 is transcriptionally active in the stem cells of highly proliferative tissues...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (18): dev188730.
Published: 28 September 2020
... to understand how neural progenitor cells generate neuronal diversity in the developing central nervous system. However, not much is known about how temporal identity is encoded in progenitors to initiate the correct transcriptional code producing the appropriate cell types for a given developmental stage...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (14): dev190330.
Published: 24 July 2020
...Brett R. Lancaster; James D. McGhee ABSTRACT We define a quantitative relationship between the affinity with which the intestine-specific GATA factor ELT-2 binds to cis -acting regulatory motifs and the resulting transcription of asp-1 , a target gene representative of genes involved...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (11): dev190231.
Published: 11 June 2020
...-dependent mRNA degradation as part of the RISC complex ( Hutvagner and Simard, 2008 ), we tested whether AGO1 depletion altered Myc mRNA levels post transcriptionally. We screened miRBase ( Griffiths-Jones, 2004 ), which contains published mature miRNA sequences from 223 species ( Kozomara and Griffiths...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (8): dev179069.
Published: 27 April 2020
... ( Franklin et al., 2019 preprint), and that it is possible for Yki/YAP/TAZ to localise to the nucleus but be transcriptionally inactive ( Parker and Struhl, 2015 ; Ege et al., 2018 ). Thus, it is overly simplistic to only assess nuclear or cytoplasmic levels of Yki/YAP/TAZ as a proxy for activity...
Journal Articles
Journal: Development
Development (2020) 147 (8): dev184259.
Published: 12 April 2020
... ( Fig. 3 ), it appears that gene activation is likely to be the major mode of differential gene expression during Drosophila spermatogenesis. On the other hand, genes with stable levels of transcripts ( Fig. S7 ) could still be regulated post-transcriptionally, which is extensively used...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (2): dev180018.
Published: 22 January 2020
... or the ability to cope with a low stress environment, but yield specific defects in coping with inescapable stress. Following these cellular and functional assays, we sought insights into molecular roles of Ars2. We have reported that Ars2 binds to Sox2 regulatory regions and transcriptionally activates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (24): dev182568.
Published: 20 December 2019
.... , Saida , K. , Fujimoto , Y. and Kataoka , H. ( 2005 ). The ecdysteroidogenic P450 Cyp302a1/disembodied from the silkworm, Bombyx mori, is transcriptionally regulated by prothoracicotropic hormone . Insect Mol. Biol.   14 , 563 - 571 . 10.1111/j.1365-2583.2005.00587.x Ohhara , Y...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev182766.
Published: 25 September 2019
... Genome organization Phase separation Transcription The cell nucleus is a crowded environment. This is easily appreciated by considering that the almost 2 m long DNA polymer that comprises the human genome is packaged into a ∼6-10 µm diameter cell nucleus along with all the biological...
Journal Articles
Journal: Development
Development (2019) 146 (12): dev180190.
Published: 24 June 2019
.... , Huang , Y. , Watson , J. A. , Economou , C. , Marek-Johnston , C. , Tomlinson , S. R. and Wilson , V. ( 2019 ). Transcriptionally dynamic progenitor populations organised around a stable niche drive axial patterning . Development   146 , dev.168161 . 10.1242/dev.168161...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (10): dev173112.
Published: 22 May 2019
... the differences we observed between cells and embryos. Before stage 7.5, the dorsal accumulation of β-Catenin establishes transcriptionally poised chromatin architecture at the promoter of sia1 , via the recruitment of the arginine methyltransferase Prmt2 ( Blythe et al., 2010 ). Consequently, barhl2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (8): dev162628.
Published: 23 April 2019
...Berta Terré; Michael Lewis; Gabriel Gil-Gómez; Zhiyuan Han; Hao Lu; Mònica Aguilera; Neus Prats; Sudipto Roy; Haotian Zhao; Travis H. Stracker ABSTRACT GEMC1 and MCIDAS are geminin family proteins that transcriptionally activate E2F4/5-target genes during multiciliogenesis, including Foxj 1...
Includes: Supplementary data