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Keywords: Toll
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Journal Articles
Journal: Development
Development (2018) 145 (9): dev156018.
Published: 25 April 2018
...Niki Anthoney; Istvan Foldi; Alicia Hidalgo ABSTRACT The membrane receptor Toll and the related Toll-like receptors (TLRs) are best known for their universal function in innate immunity. However, Toll/TLRs were initially discovered in a developmental context, and recent studies have revealed...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (16): 2907–2913.
Published: 15 August 2017
...Maira Arruda Cardoso; Marcio Fontenele; Bomyi Lim; Paulo Mascarello Bisch; Stanislav Y. Shvartsman; Helena Marcolla Araujo ABSTRACT The evolutionarily conserved Toll signaling pathway controls innate immunity across phyla and embryonic patterning in insects. In the Drosophila embryo, Toll...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (13): 2139–2146.
Published: 1 July 2010
... of a repulsive cue, Toll. We focused on two neighboring muscles, M12 and M13, which are innervated by distinct motoneurons in Drosophila . We found that Toll , which encodes a transmembrane protein with leucine-rich repeats, was preferentially expressed in M13. In Toll mutants, motoneurons that normally...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (15): 3419–3429.
Published: 1 August 2005
...Atish Ganguly; Jin Jiang; Y. Tony Ip The maternal Toll signaling pathway sets up a nuclear gradient of the transcription factor Dorsal in the early Drosophila embryo. Dorsal activates twist and snail , and the Dorsal/Twist/Snail network activates and represses other zygotic genes to form...
Journal Articles
Journal: Development
Development (2003) 130 (25): 6257–6272.
Published: 22 December 2003
... expression analysis to identify genes differentially expressed in FCs and FCMs. We employed embryos derived from Toll 10b mutants to obtain primarily muscleforming mesoderm, and expressed activated forms of Ras or Notch to induce FC or FCM fate, respectively. The transcripts present in embryos of each...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (8): 1925–1933.
Published: 15 April 2002
...Baohe Shen; James L. Manley The Drosophila Pelle kinase plays a key role in the evolutionarily conserved Toll signaling pathway, but the mechanism responsible for its activation has been unknown. We present in vivo and in vitro evidence establishing an important role for concentration-dependent...