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Keywords: Tissue homeostasis
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Journal Articles
Journal: Development
Development (2022) 149 (6): dev199363.
Published: 17 March 2022
... morphology during development, and the Myosin Vb-Rab10 interaction is essential for directional cell growth downstream of mTOR signaling. Cell size regulation Compensatory cell growth Tissue homeostasis Myosin Vb mTOR signaling Epidermis Zebrafish Tata Institute of Fundamental Research...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (14): dev193268.
Published: 19 July 2021
...Sonja D. C. Weterings; Marek J. van Oostrom; Katharina F. Sonnen ABSTRACT Despite striking parallels between the fields of developmental biology and adult tissue homeostasis, these are disconnected in contemporary research. Although development describes tissue generation and homeostasis describes...
Journal Articles
Journal: Development
Development (2020) 147 (23): dev183442.
Published: 15 December 2020
... review the findings that highlight the dynamic nature of nuclear pore complexes and their roles in many cell type-specific functions during development and tissue homeostasis. * Author for correspondence ( mdangelo@sbpdiscovery.org ) Competing interests The authors declare no competing...
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (8): 1396–1406.
Published: 15 April 2015
... heterogeneity Germ line Intestine Lineage tracing Tissue homeostasis In multicellular organisms, groups of cells specialize within tissues and organs to perform specific tasks and functions. In the course of adult life, these functional cells can become exhausted and progressively lost...
Journal Articles
Journal: Development
Development (2014) 141 (13): 2559–2567.
Published: 1 July 2014
... residing in autonomously maintained compartments facilitate this task. In this Review, we discuss stem cell behaviour during normal tissue homeostasis, regeneration and disease within the pilosebaceous unit, an integral structure of the epidermis that is responsible for hair growth and lubrication...
Journal Articles
Journal: Development
Development (2013) 140 (12): 2502–2512.
Published: 15 June 2013
...Jason H. Pomerantz; Helen M. Blau Tumor suppressors are so named because cancers occur in their absence, but these genes also have important functions in development, metabolism and tissue homeostasis. Here, we discuss known and potential functions of tumor suppressor genes during tissue...
Journal Articles
Journal: Development
Development (2012) 139 (19): 3510–3520.
Published: 1 October 2012
... examples of the recruitment of fully potent stem cells, compared with limited progenitors, are known. Here, we show that planarian stem cells directionally migrate to amputation sites during regeneration. We also show that during tissue homeostasis they are stationary. Our study not only uncovers...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2011) 138 (15): 3103–3111.
Published: 1 August 2011
... interests statement The authors declare no competing financial interests. © 2011. Stem cells Stochastic cell fate Tissue homeostasis In adults, the maintenance and repair of tissue is coordinated by stem cells, which maintain the ability to self-renew throughout adult life...
Journal Articles
Journal: Development
Development (2010) 137 (2): 213–221.
Published: 15 January 2010
.... Annu. Rev. Cell Dev. Biol. 20 , 725 - 757 . Reddien P. W. , Bermange A. L. , Murfitt K. J. , Jennings J. R. , Sánchez Alvarado A. ( 2005a ). Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (1): 183–192.
Published: 1 January 2008
... possess progenitor activity in the postnatal mammalian heart ( Beltrami et al., 2003 ; Laugwitz et al., 2005 ; Martin et al., 2004 ; Oh et al., 2003 ). However, a natural in vivo contribution of these progenitor cells to adult tissue homeostasis has not been experimentally demonstrated. Organ...
Includes: Supplementary data