... studied the development of the ventral telencephalon and thalamocortical axons, which have been previously shown to be controlled by Slit2. Remarkably, this analysis revealed that Trio knockout (KO) mice show phenotypes that bear strong similarities to the ones that have been reported in Slit2 KO mice...

...-mail: Martine.Manuel@ed.ac.uk ) 20 11 2006 © 2007. 2007 Pax6 Cortex Overexpression Autoregulation Proliferation Neurogenesis Lamination Regionalization Thalamocortical Chimeras The complexity of brain structure and function is established through the generation of numerous...

... receptor, previously shown to control topographic specificity of thalamocortical axons in the mouse somatosensory system. Using axon tracing analyses of knock-in mouse lines displaying selective mutations for the Epha4 gene, we determined for the first time which intracellular domains of an Eph receptor...