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Keywords: Tcf
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Journal Articles
Journal: Development
Development (2011) 138 (22): 4955–4967.
Published: 15 November 2011
...), and its human homolog jerky, promote interaction between the Wnt pathway transcriptional co-activators β-catenin/Armadillo and TCF to facilitate context-dependent Wnt signaling responses. Here, through the same genetic screen, we find an unanticipated requirement for Erect Wing (Ewg), the fly homolog...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (20): 4341–4350.
Published: 15 October 2011
.... A. , Kuhl M. ( 2007 ). Beta-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells . FEBS Lett. 581 , 5247 - 5254 . Arce L. , Yokoyama N. N. , Waterman M. L. ( 2006 ). Diversity of LEF/TCF action in development...
Journal Articles
Journal: Development
Development (2011) 138 (7): 1421–1432.
Published: 1 April 2011
... is transmitted via the MAPK pathway, which activates the Ci -Ets1/2 transcription factor. Targeted perturbation of Ci -TCF, a downstream factor of the canonical Wnt pathway, indicated its contribution to pigment cell differentiation Furthermore, analyses of the Ci - Tcf regulatory region revealed the involvement...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (18): 3057–3066.
Published: 15 September 2010
... of the animals and repression of aboral structures (i.e. stolons). The expression of Wnt3, Tcf and Brachyury was upregulated and became ubiquitous. Rescue experiments using Tcf RNAi resulted in normal metamorphosis and quantitatively normal Wnt3 and Brachyury expression. Isolated, decapitated polyps regenerated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (17): 2939–2949.
Published: 1 September 2010
... conserved among tetrapods and unexpectedly directed all the Emx2 expression in forebrain: caudal forebrain primordium at E8.5, dorsal telencephalon at E9.5-E10.5 and the cortical ventricular zone after E12.5. Otx, Tcf, Smad and two unknown transcription factor binding sites were essential to all...
Journal Articles
Journal: Development
Development (2006) 133 (20): 3983–3992.
Published: 15 October 2006
..., Sema3d knockdown reduces markers of migratory NCCs and disrupts NCC-derived tissues. Similarly, expression of a dominant-repressor form of TCF (ΔTCF) reduces hindbrain cell proliferation and leads to a disruption of migratory NCC markers. Moreover,expression of ΔTCF downregulates sema3d RNA expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (24): 5375–5385.
Published: 15 December 2005
...Fei Liu; Olaf van den Broek; Olivier Destrée; Stefan Hoppler Tcf/Lef transcription factors and β-catenin mediate canonical Wnt signalling, which plays remarkably diverse roles in embryonic development,stem cell renewal and cancer progression. To investigate the molecular mechanisms allowing...
Journal Articles
Journal: Development
Development (2004) 131 (19): 4725–4734.
Published: 1 October 2004
.... Based on these observations, we propose that Frodo and Dapper link Dsh and TCF to regulate Wnt target genes in a pathway parallel to that of β-catenin. † Author for correspondence (e-mail: sergei.sokol@mssm.edu ) * Present address: Department of Molecular, Cell and Developmental Biology,Mount...
Journal Articles
Journal: Development
Development (2004) 131 (12): 2899–2909.
Published: 15 June 2004
...Chris J. Thorpe; Randall T. Moon Wnt/β-catenin signaling regulates many aspects of early vertebrate development, including patterning of the mesoderm and neurectoderm during gastrulation. In zebrafish, Wnt signaling overcomes basal repression in the prospective caudal neurectoderm by Tcf homologs...
Journal Articles
Journal: Development
Development (2002) 129 (24): 5743–5752.
Published: 15 December 2002
...-catenin—Tcf complex is required for the transcription of the Xenopus nodal genes Xnr5 and Xnr6 as early as the 256-cell stage. Moreover, inhibition of β-catenin/Tcf function can block dorsal development, but only if the inhibition begins early and is maintained throughout pre-MBT stages. Dorsal...
Journal Articles
Journal: Development
Development (2002) 129 (11): 2565–2576.
Published: 1 June 2002
... TCF, enabling it to activate transcription. Though many nuclear factors have been implicated in modulating TCF/Armadillo activity, their importance remains poorly understood. This work describes a ubiquitously expressed protein, called Pygopus, which is required for Wg signaling throughout Drosophila...
Journal Articles
Journal: Development
Development (2001) 128 (11): 2063–2073.
Published: 1 June 2001
...., Pishvaian, M., Salimuddin and Byers, S. ( 1999 ). Cross-regulation of beta-catenin-LEF/TCF and retinoid signaling pathways. Curr. Biol . 9 , 1415 -1418. Frank, D. and Harland, R. M. ( 1991 ). Transient expression of XMyoD in non-somitic mesoderm of Xenopus gastrulae. Development 113...