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Development (2021) 148 (19): dev199585.
Published: 05 October 2021
...-tetrahydrocannabinol (THC) induces two hallmark HH loss-of-function phenotypes (HPE and ventral neural tube patterning defects) in Cdon mutant mice, which have a subthreshold deficit in HH signaling. THC therefore acts as a ‘conditional teratogen’, dependent on a complementary but insufficient genetic insult. In vitro...
Includes: Supplementary data