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Development (2009) 136 (4): 575–584.
Published: 15 February 2009
...Sei Kuriyama; Roberto Mayor Syndecan-4 (Syn4) is a heparan sulphate proteoglycan that is able to bind to some growth factors, including FGF, and can control cell migration. Here we describe a new role for Syn4 in neural induction in Xenopus . Syn4 is expressed in dorsal ectoderm and becomes...
Includes: Supplementary data
Helen K. Matthews, Lorena Marchant, Carlos Carmona-Fontaine, Sei Kuriyama, Juan Larraín, Mark R. Holt, Maddy Parsons, Roberto Mayor
Development (2008) 135 (10): 1771–1780.
Published: 15 May 2008
... in the direction of their target during embryonic development. We show that the proteoglycan Syndecan-4 (Syn4) is expressed in the migrating neural crest of Xenopus and zebrafish embryos. Loss-of-function studies using an antisense morpholino against syn4 show that this molecule is required for NC migration...
Includes: Multimedia, Supplementary data