...Mei-Juan Cai; Wen-Li Zhao; Yu-Pu Jing; Qian Song; Xiao-Qian Zhang; Jin-Xing Wang; Xiao-Fan Zhao Insulin inhibits transcription factor Forkhead box O (FoxO) activity, and the steroid hormone 20-hydroxyecdysone (20E) activates FoxO; however, the mechanism is unclear. We hypothesized that 20E...

...Dhaval S. Patel; Lily L. Fang; Danika K. Svy; Gary Ruvkun; Weiqing Li In C. elegans , steroid hormones function in conjunction with insulin/IGF-1-like signaling in promoting reproductive development over entry into the diapausal dauer stage. The NCR-1 and -2 (NPC1-related) intracellular cholesterol...

... epididymis and female reproductive tract. Hr39 controls the expression of specific cytochrome P450 genes and is required in females both to activate spermathecal secretion and repress male-specific courtship genes such as takeout . Thus, a pathway that, in vertebrates, controls sex-specific steroid hormone...

... ©2005. 2005 Olfaction Projection neuron Metamorphosis Pruning Steroid hormone TGFβ signaling Antennal lobe Mushroom body Lateral horn Drosophila Structural and functional changes in neuronal connectivity extending past embryogenesis and even into adult life are of great...

...Ivana Gaziova; Peter C. Bonnette; Vincent C. Henrich; Marek Jindra Steroid signaling underlies developmental processes in animals. Mutations that impair steroidogenesis in the fruit fly Drosophila melanogaster provide tools to dissect steroid hormone action genetically. The widely used temperature...

...Nathalie Renault; Kirst King-Jones; Michael Lehmann Drosophila development is coordinated by pulses of the steroid hormone 20-hydroxyecdysone (20E). During metamorphosis, the 20E-inducible Broad-Complex ( BR-C ) gene plays a key role in the genetic hierarchies that transduce the hormone signal...

...Marc R. Freeman; Anna Dobritsa; Peter Gaines; William A. Segraves; John R. Carlson Steroid hormones mediate a wide variety of developmental and physiological events in insects, yet little is known about the genetics of insect steroid hormone biosynthesis. Here we describe the Drosophila dare gene...

...Karen Lunde; Brian Biehs; Ulrich Nauber; Ethan Bier ABSTRACT The neighboring homologous knirps ( kni ) and knirpsrelated ( knrl ) genes in Drosophila encode transcription factors in the steroid hormone receptor superfamily. During early embryogenesis, kni functions as a gap gene to control...

...Catherine A. Brennan; Michael Ashburner; Kevin Moses ABSTRACT In Drosophila , secretion of the steroid hormone ecdysone from the prothoracic ring gland coordinates and triggers events such as molting and metamorphosis. In the developing Drosophila compound eye, pattern formation and cell-type...

... 1989 by Company of Biologists 1989 steroid hormone thyroid receptor transcriptional control Drosophila knirps In the 1930s T. H. Morgan theorized that the process of development occurred by the differential expression of small invisible entities called genes and that expression...

... and growth factors. Little is known, however, about the expression of cellular proto-oncogenes in cells induced to proliferate in vivo by steroid hormones. Experiments reported here indicate that when cells of the immature chicken oviduct are induced to undergo rapid in vivo proliferation by application...