1-20 of 24
Keywords: Spermiogenesis
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2023) 150 (13): dev201606.
Published: 30 June 2023
.... Using a combination of cell sorting and DNA methyl-seq capture, we generated a stage-specific mapping of DNAme in nine populations of differentiating germ cells from perinatal life to spermiogenesis. DNAme was found to reach its lowest level at gestational day 18, the last demethylated coding regions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (9): dev201501.
Published: 12 May 2023
... DOT1L- or MLLT10-deficient mice. These results demonstrate that H3K79 methylation promotes histone replacement during spermiogenesis. Total protein extract from testis or cultured cells was prepared by homogenization in five volumes of protein extraction buffer [62.5 mM Tris-HCl (pH 6.8), 3% SDS, 10...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (9): dev201497.
Published: 12 May 2023
... exchange, including genes encoding transition proteins, protamines and the testis-specific bromodomain protein BRDT. Spermiogenesis Fertility Histone Chromatin Protamine DOT1L National Institutes of Health DP2HD108774 R01HD098128 G. Harold and Leila Y. Mathers Foundation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (18): dev200696.
Published: 15 September 2022
... in spermiogenesis, resulting in reduced H3K27me3 in normal spermatozoa. Therefore, the absence of epigenetic remodelling, presumably mediated by histone turnover during spermiogenesis, leads to dysregulation of chromatin accessibility and transcription in ROSI embryos. Thus, our results unveil a molecular logic...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2022) 149 (16): dev200499.
Published: 22 August 2022
...Naila Umer; Sharang Phadke; Farhad Shakeri; Lena Arévalo; Keerthika Lohanadan; Gregor Kirfel; Marc Sylvester; Andreas Buness; Hubert Schorle ABSTRACT Profilin 4 ( Pfn4 ) is expressed during spermiogenesis and localizes to the acrosome-acroplaxome-manchette complex. Here, we generated PFN4-deficient...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2022) 149 (15): dev200951.
Published: 4 August 2022
.... The spermatozoids of bryophytes harbor distinctive morphological characteristics, including a cell body with a helical shape and two flagella. During spermiogenesis, the shape and cellular contents of the spermatids are dynamically reorganized. However, the reorganization patterns of each organelle remain obscure...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (12): dev199573.
Published: 16 June 2022
... and neurons, developing spermatids display significant uncoupling of transcription and translation for delayed translation. Therefore, spermiogenesis represents an excellent in vivo model for investigating the mechanism underlying uncoupled transcription and translation. Through full-length poly(A) deep...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (24): dev199922.
Published: 15 December 2021
... of Biologists Ltd 2021 Summary: Analysis of a graded series of KATNB1 loss-of-function models reveals that katanin proteins are required to regulate the vast majority of microtubule-based processes in male germ cell development. Male fertility Male infertility Microtubules Spermiogenesis...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2021) 148 (11): dev199414.
Published: 8 June 2021
... spermatids, transition from a meiotic gene-expression program to a post-meiotic and spermatid gene expression program related to DNA condensation is impaired, suggesting that EWSR1 plays an important role in regulation of spermiogenesis-related mRNA synthesis necessary for spermatid differentiation...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2020) 147 (2): dev181057.
Published: 22 January 2020
.... In the present study, we investigated the role of A-kinase anchoring protein 3 (AKAP3) during mouse spermiogenesis, using both mouse genetics and proteomics. It was found that AKAP3 is essential for the formation of the specific subcellular structure of the sperm flagellum, motility of sperm and male fertility...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (11): dev164723.
Published: 30 May 2018
...Daoqin Zhang; Dan Xie; Xiwen Lin; Longfei Ma; Jian Chen; Daoqi Zhang; Yang Wang; Shuguang Duo; Yanmin Feng; Chunwei Zheng; Binjie Jiang; Yan Ning; Chunsheng Han ABSTRACT The postmeiotic development of male germ cells, also known as spermiogenesis, features the coordinated expression of a large...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2017) 144 (18): 3253–3263.
Published: 15 September 2017
...-regulated mechanism generating asymmetrical division in cortical precursors . Cell Rep.   6 , 400 - 414 . 10.1016/j.celrep.2013.12.026 Fabian , L. and Brill , J. A. ( 2012 ). Drosophila spermiogenesis: Big things come from little packages . Spermatogenesis   2 , 197 - 212 . 10.4161...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (5): 921–930.
Published: 1 March 2015
...Wei Li; Waixing Tang; Maria E. Teves; Zhengang Zhang; Ling Zhang; Hongfei Li; Kellie J. Archer; Darrell L. Peterson; David C. Williams, Jr; Jerome F. Strauss, III; Zhibing Zhang A key event in the process of spermiogenesis is the formation of the flagella, which enables sperm to reach eggs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (19): 3583–3589.
Published: 1 October 2012
... with the failure of acrosomal expansion during spermiogenesis and resulted in the degeneration and disappearance of the acrosome in mature spermatozoa. Thus, these findings clarify part of the cascade leading to globozoospermia. * Author for correspondence ( okabe@biken.osaka-u.ac.jp ) Competing...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (3): 373–382.
Published: 1 February 2009
...Jing Zhou; Ya-Rui Du; Wei-Hua Qin; Ye-Guang Hu; Yan-Nv Huang; Lan Bao; Daishu Han; Ahmed Mansouri; Guo-Liang Xu During spermiogenesis, round spermatids are converted into motile sperm in mammals. The mechanisms responsible for sperm morphogenesis are poorly understood. We have characterized a novel...
Includes: Supplementary data