1-20 of 22
Keywords: Spermatogonia
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2023) 150 (13): dev201606.
Published: 30 June 2023
... and mapping of DNA methylation was generated at key developmental stages of spermatogenesis in rat. DNA methylation Epigenetic reprogramming Methyl-seq capture Gonocytes Spermatogenesis Spermatogonia Spermatids Spermatozoa Spermiogenesis Rat Fonds de Recherche du Quebec http...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2023) 150 (10): dev201430.
Published: 24 May 2023
.... To investigate this, we analyzed the expression profile of spermatogonial markers during the seminiferous epithelial cycle in cynomolgus monkeys and compared the results with human data. We found that in cynomolgus monkeys, as in humans, undifferentiated spermatogonia are largely quiescent, and the few engaged...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2022) 149 (22): dev200713.
Published: 16 November 2022
...Oleksandr Kirsanov; Taylor Johnson; Taylor Malachowski; Bryan A. Niedenberger; Emma A. Gilbert; Debajit Bhowmick; P. Hande Ozdinler; Douglas A. Gray; Kelsey Fisher-Wellman; Brian P. Hermann; Christopher B. Geyer ABSTRACT In mammalian testes, premeiotic spermatogonia respond to retinoic acid...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (8): dev184655.
Published: 12 April 2020
... and progenitors. Here, using mouse models, we explored the role of RNA-binding proteins (RBPs) in regulation of the biological activities of this population. Proteins bound to polyadenylated RNAs in primary cultures of undifferentiated spermatogonia were captured with oligo (dT)-conjugated beads after UV...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (21): dev180273.
Published: 6 November 2019
... elevated kinase activity, which underlies these differentiation defects. Our results demonstrate that precise regulation of CDK2 kinase activity in male germ cell development is crucial for the gonocyte-to-spermatogonia transition and long-term spermatogenic homeostasis. * Author for correspondence...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2018) 145 (15): dev161323.
Published: 13 August 2018
... products. In addition to ICBs, spermatogonia exhibit multiple thin cytoplasmic projections. Here, we have explored the nature of these projections in mice and find that they are dynamic, span considerable distances from their cell body (≥25 μm), either terminate or physically connect multiple adjacent...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (19): 3430–3439.
Published: 1 October 2017
.... Despite this crucial role, the molecular signature, kinetic behavior and regulation of human spermatogonia are poorly understood. Using human testis biopsies with normal spermatogenesis and by studying marker protein expression, we have identified for the first time different subpopulations...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (17): 3022–3030.
Published: 1 September 2017
... Spermatogonia Spermatogonial stem cells Stem cells Spermatogenesis, the process that generates spermatozoa (mature male gametes), takes place in the wall of the seminiferous tubules and involves a multitude of sequential cell types ( Fig. 1 ). First, there are undifferentiated spermatogonia, among...
Journal Articles
Journal: Development
Development (2017) 144 (4): 624–634.
Published: 15 February 2017
... the stem cell to the immediate progenitor state requires downregulation of Id4 coincident with a major change in the transcriptome. Collectively, our results demonstrate that the level of ID4 is predictive of stem cell or progenitor capacity in spermatogonia and dictates the interface of transition between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1582–1592.
Published: 1 May 2015
..., the mechanisms that operate in mouse spermatogenesis are unknown because undifferentiated spermatogonia (A undiff ) are motile and intermingle with differentiating cells in an ‘open’ niche environment of seminiferous tubules. A undiff include glial cell line-derived neurotrophic factor receptor α1 (GFRα1...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (10): 1734–1743.
Published: 15 May 2012
.... 12 3 2012 © 2012. Spermatogonia Self-renewal FGF2 Spermatogonial stem cells (SSCs) have the unique ability to undergo self-renewal division and to support spermatogenesis throughout life. Although SSCs are present in low numbers in the testis (0.02-0.03% of the total...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (16): 3367–3376.
Published: 15 August 2011
... by detaching from the hub. Following starvation-induced GSC loss, GSC numbers are restored by symmetric renewals. Furthermore, upon more severe (genetically induced) GSC loss, both symmetric renewal and de-differentiation (where interconnected spermatogonia fragment into pairs while moving towards...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (1): 117–122.
Published: 1 January 2005
..., and the maturation process, from epiblast cells through PGCs to postnatal spermatogonia, can occur in the postnatal testicular environment. Primordial germ cell transplantation techniques will also provide a novel tool to assess the developmental potential of PGCs, such as those manipulated in vitro or recovered...
Journal Articles
Journal: Development
Development (2002) 129 (14): 3359–3365.
Published: 15 July 2002
... cells alone, indicating that the feeder cells stimulate proliferation of spermatogonia. When cultured germ cells/sperm with the feeders were used for in vitro fertilization, normal embryos were obtained. Addition of the thymidine analogue 5-bromo-2′-deoxyuridine (BrdU) into culture medium resulted...
Journal Articles
Journal Articles