... ‡ These authors contributed equally to the work 5 9 2022 25 4 2023 © 2023. Published by The Company of Biologists Ltd 2023 http://www.biologists.com/user-licence-1-1/ Computational method Rare cell types Single-cell sequencing Helmholtz Association https://dx.doi.org...

.... , Balachandran , S. , Pachchek , S. et al. ( 2022 ). Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state . Brain 145 , 964 - 978 . 10.1093/brain/awab446 Sommeijer , J.-P. and Levelt , C. N. ( 2012 ). Synaptotagmin-2...

... and machine learning algorithms to define neuronal developmental trajectories. In vitro differentiation Machine learning Neuronal development Neuronal differentiation protocols Neuronal replacement therapy Single-cell sequencing The goal of neuronal replacement therapy is to provide...

... and our evolutionary history. Human development Single-cell sequencing Epigenetics Organoid Evolution Developmental biology research has a long history of studying model organisms such as the fruit fly Drosophila melanogaster , focusing mainly on early embryogenesis. One major...

... Highlighted article: Gene expression analyses reveal that zebrafish epicardial cells are heterogeneous and identify many new epicardial markers, including Caveolin 1, which is shown to be essential for heart regeneration. Heart regeneration Epicardium Single-cell sequencing Caveolin-1 Zebrafish...