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Keywords: Secretory pathway
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Journal Articles
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Neural development
Journal: Development
Development (2017) 144 (10): 1851–1862.
Published: 15 May 2017
... metamorphosis. However, it is unknown whether the secretory pathway plays a role in dendrite pruning. Here, we show that the small GTPase Arf1, an important regulator of the secretory pathway, is specifically required for dendrite pruning of ddaC/D/E sensory neurons but dispensable for apoptosis of ddaF neurons...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (19): 3540–3548.
Published: 1 October 2016
... trafficking and thus impairing eggshell formation and the oocyte-to-embryo transition. Small molecule Oocyte-to-embryo transition Secretory pathway C. elegans To find potential target molecules or pathways through which C22 acts, we performed a forward genetic screen to recover suppressors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (14): 3018–3027.
Published: 15 July 2013
... proteins involved in the regulation of a wide range of cellular processes during development and adult tissue homeostasis. In this study, we identify an unanticipated role of Catsup in regulating the trafficking of membrane proteins within the secretory pathway. We find that Notch, EGFR and APPL...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (19): 3419–3425.
Published: 1 October 2007
... the correct delivery of secretory pathway components, such as the TGFαhomolog Gurken, to the plasma membrane. Moreover, in the absence of Drab6, osk mRNA localization and the organization of microtubule plus-ends at the posterior of the oocyte were both severely affected. Our results point to a possible...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (12): 2743–2758.
Published: 15 June 2005
...; CrebA is required throughout embryogenesis and Fkh is required only during late embryonic stages. As Fkh is required to maintain late CrebA expression in the salivary gland, Fkh probably works through CrebA to affect secretory pathway gene expression. In support of these regulatory interactions, we show...
Includes: Supplementary data