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Keywords: Sclerotome
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Journal Articles
Journal: Development
Development (2015) 142 (10): 1733–1744.
Published: 15 May 2015
... 108 , 9484 - 9489 . 10.1073/pnas.1007566108 Christ , B. , Huang , R. and Scaal , M. ( 2004 ). Formation and differentiation of the avian sclerotome . Anat. Embryol. (Berl) 208 , 333 - 350 . 10.1007/s00429-004-0408-z Christ , B. , Huang , R. and Scaal , M...
Journal Articles
Journal: Development
Development (2014) 141 (20): 3848–3858.
Published: 15 October 2014
... using such small molecules were chondrogenic in vitro , and expressed trunk paraxial mesoderm markers such as Tcf15 and Meox1, and somite markers such as Uncx, but failed to express sclerotome markers such as Pax1. Induction of the osteochondrogenically committed sclerotome from somite requires sonic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (5): 1005–1014.
Published: 1 March 2011
... the effects of BMP signaling on the specification of the sclerotome. We confirmed reduction of Pax1 and Pax9 expression in Nog mutants, but found that Nog ; Grem1 double mutants completely fail to initiate sclerotome development. Furthermore, Nog mutants that also lack one allele of Grem1 exhibit a dramatic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (1): 99–106.
Published: 1 January 2006
...: mbronner@caltech.edu ) 27 10 2005 © 2006. 2006 Trunk neural crest migration Sclerotome Neuropilin 2 Semaphorin 3F Mouse Chick The neural crest is a multipotent population of migratory cells that gives rise to a wide variety of different lineages in vertebrates...
Journal Articles
Journal: Development
Development (2005) 132 (3): 515–528.
Published: 1 February 2005
... compartments, the myotome and sclerotome, in response to signals secreted from surrounding tissues. As the somite matures, the tendon lineage is established within the dorsolateral sclerotome, adjacent to and beneath the myotome. We examine interactions between the three lineages by observing tendon...
Journal Articles
Journal: Development
Development (2004) 131 (16): 3885–3896.
Published: 15 August 2004
...Ava E. Brent; Clifford J. Tabin During somite development, a fibroblast growth factor (FGF) signal secreted from the myotome induces formation of a scleraxis ( Scx )-expressing tendon progenitor population in the sclerotome, at the juncture between the future lineages of muscle and cartilage. While...
Journal Articles
Journal: Development
Development (2004) 131 (3): 525–537.
Published: 1 February 2004
...: Hubrecht Laboratory, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands 29 10 2003 © 2004. 2004 Hyaluronan Has Dg42 Rac1 Cell migration Convergence extension Adaxial cells Slow muscle Sclerotome Germ cells Metastasis Zebrafish Hyaluronan (HA) is a linear polysaccharide...
Journal Articles
Journal: Development
Development (2003) 130 (21): 5103–5111.
Published: 1 November 2003
.... In the early chicken embryo CPZ is initially expressed throughout the somites and subsequently becomes restricted to the sclerotome. To initiate a functional analysis of CPZ, a CPZ producing retroviral vector was applied to the presomitic mesoderm at the level of the future wing. This resulted in a loss...
Journal Articles
Journal: Development
Development (2003) 130 (3): 473–482.
Published: 1 February 2003
... and their target genes remain to be elucidated. We show, by analyzing Pax1;Pax9 double mutant mice, that expression of Bapx1 in the sclerotome requires the presence of Pax1 and Pax9, in a gene dose-dependent manner. By using a retroviral system to overexpress Pax1 in chick presomitic mesoderm explants, we show...
Journal Articles
Journal: Development
Development (2002) 129 (16): 3851–3860.
Published: 15 August 2002
... vertebral column cellular and developmental biology. In this study, we characterized alignment of somites and vertebrae, distribution of individual sclerotome progeny along the anteroposterior axis and development of the axial skeleton in zebrafish. Our clonal analysis of zebrafish sclerotome shows...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2187–2198.
Published: 15 June 2001
... the sclerotomal portion of the myotome ( Fig. 3 D). This position is adopted by ingrowing second-wave myofibers relative to pre-existing pioneers, which always remain apposed to the superficial, dermal side of the myotome ( Kahane et al., 1998b ). In addition, FREK mRNA signal is also apparent in a discrete...