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Keywords: Schwann cell
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (17): dev200640.
Published: 5 September 2022
...Aya Mikdache; Marie-José Boueid; Emilie Lesport; Brigitte Delespierre; Julien Loisel-Duwattez; Cindy Degerny; Marcel Tawk ABSTRACT Schwann cells (SCs) migrate along peripheral axons and divide intensively to generate the right number of cells prior to axonal ensheathment; however, little is known...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (17): 3114–3125.
Published: 1 September 2017
... and negative regulators within the axon and Schwann cell function to ensure the correct onset and progression of myelination during both development and following peripheral nerve injury and repair. The Sox2 transcription factor is well known for its roles in the development and maintenance of progenitor...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3188–3197.
Published: 15 September 2015
...Motoharu Sakaue; Maya Sieber-Blum We show that highly pure populations of human Schwann cells can be derived rapidly and in a straightforward way, without the need for genetic manipulation, from human epidermal neural crest stem cells [hEPI-NCSC(s)] present in the bulge of hair follicles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1749–1756.
Published: 15 April 2014
... of Biologists Ltd 2014 Evolution and development Myelination Leucine-rich glioma-inactivated ADAM23 Schwann cell Mouse Dynamic cell-cell interactions determine key morphological and functional properties of the nervous system during ontogeny and adult life. The formation and dynamics...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1553–1561.
Published: 1 April 2014
... saltatory propagation of action potentials along the axon and is an essential prerequisite for the normal functioning of the nervous system. During peripheral nervous system (PNS) development, myelin-forming Schwann cells (SCs) generate radial lamellipodia to sort and ensheath axons. This process requires...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (4): 740–748.
Published: 15 February 2012
... associate with terminal Schwann cell processes to form encapsulated lanceolate nerve endings of rapidly adapting mechanoreceptors. The molecular basis for piloneural development, maintenance and function is poorly understood. Here, we show that Nefh-expressing glutamatergic neurons represent a major...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (21): 4639–4648.
Published: 1 November 2011
...Julie R. Perlin; Mark E. Lush; W. Zac Stephens; Tatjana Piotrowski; William S. Talbot During peripheral nerve development, each segment of a myelinated axon is matched with a single Schwann cell. Tight regulation of Schwann cell movement, proliferation and differentiation is essential to ensure...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2673–2680.
Published: 1 July 2011
...Kelly R. Monk; Kazuo Oshima; Simone Jörs; Stefan Heller; William S. Talbot In peripheral nerves, Schwann cells form the myelin sheath that insulates axons and allows rapid propagation of action potentials. Although a number of regulators of Schwann cell development are known, the signaling pathways...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (21): 3643–3649.
Published: 1 November 2010
... lateral line nerve in zebrafish initially grows in the epidermis and then rapidly transitions across the epidermal basement membrane into the subepidermal space. Our experiments indicate that Schwann cells, which myelinate axons in the PNS, are required to reposition the nerve. In mutants lacking Schwann...
Journal Articles
Journal: Development
Development (2007) 134 (18): 3271–3281.
Published: 15 September 2007
... disturbed in both mutants. Unique requirements were additionally detected for the novel transactivation domain in satellite glia differentiation and during Schwann cell myelination, whereas DNA-dependent dimerization was needed for immature Schwann cells to enter the promyelinating stage. These two...
Journal Articles
Journal: Development
Development (2002) 129 (1): 155–166.
Published: 1 January 2002
...Julien Ghislain; Carole Desmarquet-Trin-Dinh; Martine Jaegle; Dies Meijer; Patrick Charnay; Monique Frain In Schwann cells (SC), myelination is controlled by the transcription factor gene Krox20 / Egr2 . Analysis of cis -acting elements governing Krox20 expression in SC revealed the existence...