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Keywords: Ripply3
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Journal Articles
Journal: Development
Development (2012) 139 (6): 1213–1224.
Published: 15 March 2012
... expression and formation of the pre-placodal ectoderm (PPE). RARα2 signaling induces key pre-placodal genes and establishes the posterolateral borders of the PPE. RAR signaling upregulates two important genes, Tbx1 and Ripply3 , during early PPE development. In the absence of RIPPLY3, TBX1 is required...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (2): 339–348.
Published: 15 January 2011
.... A typical developmental disorder of the pharyngeal apparatus is the 22q11 deletion syndrome (22q11DS), for which Tbx1 is responsible. Here, we show that Ripply3 can modulate Tbx1 activity and plays a role in the development of the pharyngeal apparatus. Ripply3 expression is observed in the pharyngeal...
Includes: Supplementary data