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Development (2022) 149 (9): dev198184.
Published: 6 May 2022
... , F. , Liao , Y. et al. ( 2013 ). Retinoid signaling in progenitors controls specification and regeneration of the urothelium . Dev. Cell 26 , 469 - 482 . 10.1016/j.devcel.2013.07.017 Georgas , K. M. , Armstrong , J. , Keast , J. R. , Larkins , C. E. , McHugh...
Development (2012) 139 (5): 843–858.
Published: 1 March 2012
.... * Authors for correspondence ( email@example.com ; firstname.lastname@example.org ) Competing interests statement The authors declare no competing financial interests. © 2012. Retinoids Retinoic acid Retinol dehydrogenase (RDH) Retinaldehyde dehydrogenase (RALDH) CYP26 Hindbrain Forebrain...
Development (2011) 138 (10): 2089–2097.
Published: 15 May 2011
... ureters ( Fig. 1F ). This is a surprising finding because ectopic ureters have not been associated previously with ND defects. Our previous studies reveal that Ret expression in the urinary tract depends on Gata3 and retinoid signaling, raising the possibility that these pathways might also...
Development (2009) 136 (4): 665–676.
Published: 15 February 2009
..., London NW7 1AA, UK ‡ Present address: Department of Developmental Biology, CNRS URA 2578,Pasteur Institute, 25 rue du Dr Roux, 75724 Cedex 15, Paris, France 24 11 2008 © 2009. 2009 Retinoids Gastrulation Neurogenesis Spinal cord Somites Sonic hedgehog Gli Fibroblast...
Includes: Supplementary data
Development (2009) 136 (2): 231–240.
Published: 15 January 2009
... northerns. Densitometry analysis showed a 5-fold increase of Nolz1 expression in explants exposed to retinol( Fig. 1B ). Consistent with a role for RA signals in regulating Nolz1 expression, electroporation of constructs expressing RAR403, a potent dominant-negative retinoid receptor that disrupts RA...
Includes: Supplementary data
Development (2006) 133 (2): 351–361.
Published: 15 January 2006
... ) * These authors contributed equally to this work 9 11 2005 © 2006. 2006 Retinoids Forebrain development Eye development Neural crest Telencephalon Diencephalon Optic vesicle Pituitary Sonic hedgehog FGF Mouse Aldh1a2 The embryonic forebrain...
Karen Niederreither, Julien Vermot, Isabelle Le Roux, Brigitte Schuhbaur, Pierre Chambon, Pascal Dollé
Development (2003) 130 (11): 2525–2534.
Published: 1 June 2003
... to a lack of guidance from the pouch endoderm ( Vitelli et al.,2002 ). * Author for correspondence (e-mail: email@example.com ) 24 2 2003 © 2003. 2003 Retinoids Branchial arches Pharyngeal endoderm DiGeorge syndrome Hirschprung's disease Mouse mutant...
Development (2003) 130 (10): 2039–2050.
Published: 15 May 2003
...Aida Halilagic; Maija H. Zile; Michèle Studer Retinoids, and in particular retinoic acid (RA), are known to induce posterior fates in neural tissue. However, alterations in retinoid signalling dramatically affect anterior development. Previous reports have demonstrated a late role for retinoids...
Suzan Abu-Abed, Pascal Dollé, Daniel Metzger, Caroline Wood, Glenn MacLean, Pierre Chambon, Martin Petkovich
Development (2003) 130 (7): 1449–1459.
Published: 1 April 2003
... downregulation of WNT3A and FGF8 signaling pathways by eliminating ectopic RA in gastrulating tail bud mesoderm. Gastrulation Tail bud Cytochrome P450 Homeotic transformations Mouse mutant Retinoids Retinoic acid Teratogenesis Spina bifida Caudal regression Cyp26a1 RARγ Wnt3a Brachyury...
Development (2002) 129 (22): 5103–5115.
Published: 15 November 2002
... treatments at these stages. We demonstrated by in ovo electroporation of a dominant negative retinoid receptor construct( dnRAR ) that retinoid signaling is required to initiate expression. Elevating CDX activity by ectopic expression of an activated form of a Xenopus Cdx gene ( XcadVP16 ) in the hindbrain...
Development (2002) 129 (15): 3563–3574.
Published: 1 August 2002
... development Raldh2 Retinaldehyde dehydrogenase Retinoids Sonic hedgehog Vertebrate limb growth and patterning is controlled by two integrated epithelial-mesenchymal signaling centers (for review, see Johnson and Tabin, 1997 ). One such region is the zone of polarizing activity (ZPA), the mesoderm...
Development (2001) 128 (13): 2451–2460.
Published: 1 July 2001
...@mpihan.mpg.de ) 17 4 2001 © 2001. 2001 FGF FGFR Protein kinase C RACK1 Retinoids Sonic hedgehog Chick Numerous signaling molecules that regulate vertebrate limb development have been identified including sonic hedgehog (SHH), bone morphogenetic proteins (BMPs), fibroblast growth...
Development (1988) 103 (Supplement): 31–40.
Published: 1 September 1988
... of the face, for example, the midpoint of the upper beak, are not known. Vitamin A derivatives, collectively known as retinoids, affect the development of the face of chick embryos and lead to a specific facial defect. Upper beak development is inhibited but the lower beak develops normally. The response...
Development (1986) 97 (1): 239–250.
Published: 1 September 1986
... receptor for RA, namely cytoplasmic retinoic acid-binding protein (CRABP), from the cells of the chick limb bud. It is present from stages 20–35 at similar levels and has an apparent K d of 140–280 nM. In competition experiments with other retinoids Ro 13-7410 was found to be the most effective...
Development (1986) 92 (1): 165–182.
Published: 1 March 1986
...Emile Lheureux; Stephen D. Thoms; Frederick Carey The effects of two vitamin A analogues, retinol palmitate and retinoic acid, on pattern formation during limb regeneration in larvae of two European newts, P. waltl and T. vulgaris are described. The response of the regenerating limb to retinoid...
Development (1986) 91 (1): 19–34.
Published: 1 February 1986
... regenerates. Thus, there is a marked difference in response to vitamin A between developing and regenerating limbs. The implications of this observation are discussed especially with respect to the underlying morphogenetic mechanisms. vitamin A retinoids limb development limb regeneration axolotl...
Development (1986) 91 (1): 35–53.
Published: 1 February 1986
... of developing limbs was clearly different from regenerating limbs. Hypotheses which might explain the results were discussed and a hypothesis which, proposed a dual action of vitamin A affecting both the cell cycle and the mechanism of pattern regulation was proposed. vitamin A retinoids limb development...