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Keywords: Redundancy
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Journal Articles
Journal: Development
Development (2008) 135 (4): 637–646.
Published: 15 February 2008
... receptor αexpression is furthermore sufficient to explain the observed phenotype, as PDGF is both an important survival factor and migratory cue for oligodendrocyte precursors. We thus conclude that Sox9 and Sox10 are required in a functionally redundant manner in oligodendrocyte precursors for PDGF...
Journal Articles
Journal: Development
Development (2006) 133 (15): 2875–2886.
Published: 1 August 2006
... Redundancy Glia Oligodendrocyte Neural crest The three vertebrate group E Sox proteins Sox8, Sox9 and Sox10 probably arose through gene duplication events from a single ancestral gene. These events must have occurred early during vertebrate evolution, as they are present in all vertebrates...
Journal Articles
Journal: Development
Development (2005) 132 (7): 1477–1485.
Published: 1 April 2005
... of Biology, Yonsei University, Sinchon 134,Seoul, Korea 19 1 2005 ©2005. 2005 Trichomes Cell shape Redundancy GLABRA1 (GL1) One important evolutionary mechanism that creates new gene functions is the duplication and functional diversification of genes. In principle...
Journal Articles
Journal: Development
Development (2004) 131 (10): 2349–2358.
Published: 15 May 2004
... was transiently delayed at early postnatal times. Sox8-deficient mice thus exhibited a similar, but less severe phenotype than did Sox10-deficient mice. Terminal oligodendrocyte differentiation was dramatically delayed in Sox8-deficient mice with only a single functional Sox10 allele hinting at redundancy between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (1999) 126 (15): 3449–3459.
Published: 1 August 1999
... protein of 962 amino acids. We demonstrate that lin-36 functions in and is expressed in the vulval precursor cells, establishing that the lin-36 pathway is involved in intercellular signaling. We also report that the lin-36 pathway and/or another pathway that is functionally redundant with the lin-36...
Journal Articles
Journal: Development
Development (1997) 124 (13): 2507–2513.
Published: 1 July 1997
... have a unique function in vivo. We previously showed that targeting myogenin into the Myf5 locus ( Myf5 myg-ki ) rescued the rib cage truncation in the Myf5-null mutant, hence demonstrating functional redundancy between Myf5 and myogenin in skeletal morphogenesis. Here we present the results...
Journal Articles
Journal Articles
Journal: Development
Development (1993) 118 (2): 297–324.
Published: 1 June 1993
... fates, Y promotes some posterior fates, and the B.a progeny promote posterior fates. Several of these cues are redundant. By ablating combinations of cells we have deduced how these signals may act in concert to specify the fates of the B.a progeny. We propose that fate specification in these pairs...