... of chemoattraction or chemorepulsion. Whole-mount in situ hybridisation was performed on E11-12 rat embryos or E10-13 mouse embryos, or on E4 chick embryos. The Islet 1 probe was a 1.5 kb rat fragment kindly provided by T. Jessell. The Met probe was transcribed from two mouse Met fragments (nucleotides...

... nervous system craniofacial development ontogenesis rat embryo That retinoids are essential for normal embryogenesis has been known for over three quarters of a century. Animal feeding trials identified vitamin A (the prohormone retinol) as essential for normal development. Vitamin A deficiency...

... cells. transmitter phenotype ciliary neurotrophic factor LIF tyrosine hydroxylase sensory ganglia rat embryo Primary sensory neurons exhibit markedly diverse neurochemical properties, including multiple neuroactive peptides, monoamines and amino acid transmitters ( Hökfelt et al., 1976...

... ganglia remain weakly NGFR mRNA-labeled in the posthatch animal. In the rat embryo, NGFR immunoreactivity is present in the auditory placode at E9, in the periotic mesenchyme at E9 –10, and in the medial half of the otocyst at E10 –11. At E12, epithelial NGFR expression becomes restricted anteriorly...

...). The results are in agreement with our data. © 1991 by Company of Biologists 1991 heart cardiac development cardiac troponin I cDNA slow skeletal troponin I rat embryo The troponin complex, which controls the interaction of thick and thin filaments in sarcomeric muscles in response...

... and Medicine, University of Melbourne, Parkville, Victoria 3052, Australia © 1990 by Company of Biologists 1990 insulin-like growth factors IGF-II receptor rat embryo mannose-6-phosphate mRNA protein The mannose-6-phosphate receptor is involved in the intracellular transport...

... 1989 primary myotubes secondary myotubes insertion myotendinous junction ultrastructure rat embryo In adult skeletal muscles, contractile force exerted by the myofilaments is transmitted to the dense collagenous connective tissue of the tendon (and thence to the skeleton...

... 1988 intestine ECM production rat embryo chick embryo epithelial–mesenchymal interactions basement membrane Differentiation of the intestinal epithelium during development is closely associated with ordered sequence of morphogenetic events (for a review, see Kedinger et al . 1986...

...S. K. L. Ellington ABSTRACT The glucose metabolism and embryonic development of rat embryos during organogenesis was studied using embryo culture. Glucose uptake and embryonic growth and differentiation of 10·5-day explants (embryos + membranes) were limited by the decreasing glucose concentration...

...J. J. Ross; M. J. Duxson; A. J. Harris ABSTRACT Numbers of myoblasts, primary myotubes and secondary myotubes in developing rat embryo hindlimb IVth lumbrical muscles were counted at daily intervals up until the time of birth, using electron mi-croscopy. Motoneurone death at the spinal cord level...

... ethanol yolk-sac function teratogenesis pinocytosis proteolysis rat embryo Excessive ingestion of ethanol, by either pregnant women or by pregnant experimental animals, is known to induce a characteristic pattern of developmental defects known as the fetal alcohol syndrome ( Abel, 1982...

...M.-D. Nagel; J. Nagel ABSTRACT The development of splenic erythroid colony-forming cells from rat embryos in the last 4 days of intrauterine life was examined after 2 and 7 days in a methylcellulose culture system. The number of 2- and 7-day erythroid colonies decreased sharply between...

... Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA 06 10 1986 © 1987 by Company of Biologists 1987 zinc deficiency eye development teratogenesis rat embryo The teratogenicity of zinc deficiency was first demonstrated by Turk and coworkers...

...). Basal lamina (arrows) and mesenchyme (m) are marked. 1:6000. Fig. 6. (A) Rat embryo, late day 12, untreated, showing a hindlimb with smooth peridermal surface and apical ridge (arrows). ×55. (B) Embryo 12 h after treatment. Peridermal layer is completely missing. Some peridermal cells...

...Gillian M. Morriss-Kay; Fiona Tuckett; Michael Solursh ABSTRACT Day 9 rat embryos (late presomite stage with cranial neural plate or very early neural folds) were cultured for various periods of time from 6–48 h in medium containing 20TRUml -1 Streptomyces hyaluronidase. Exposure to the enzyme...

... 27 , 683 – 684 . 10.1007/BF02136960 Levak-Švajger , B. & Švajger , A. ( 1974 ). Investigation on the origin of the definitive endoderm in the rat embryo . J. Embryol. exp. Morph . 32 , 445 – 459 . Levak-Švajger , B. & Švajger , A. ( 1979 ). Course...

...Martin J. Smedley; Martin Stanisstreet ABSTRACT The role of calcium in neurulation in mammalian embryos has been studied by culturing rat embryos at 10·4 days of gestation, when the cephalic neural folds have elevated but not fused, in serum containing cytoskeletal inhibitors or calcium antagonists...

...Carolyn L. Williams; Paul K. Priscott; I. T. Oliver; George C. T. Yeoh ABSTRACT The uptake of [ 3 H]leucine by the rat yolk sac and embryo and the subsequent synthesis of albumin and transferrin have been studied in whole embryo culture. Rat embryos of 12 days gestation were used in all experiments...

...Martin J. Smedley; Martin Stanisstreet ABSTRACT The role of calcium in neurulation in rat embryos has been studied. Rat embryos at 10-4 days of gestation, when the cephalic neural folds have elevated but not fused, have been cultured in various media, and the effects of these media...

...Fiona Tuckett; Gillian M. Morriss-Kay ABSTRACT The morphogenesis of rhombomeres (neuromeres) caudal to the preotic sulcus during neurulation in rat embryos is described. A model is proposed to explain the development of the characteristic neuromeric sulci and interneuromeric gyri based...