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Keywords: RPE
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Journal Articles
Journal: Development
Development (2015) 142 (14): 2487–2498.
Published: 15 July 2015
...Reut Ohana; Benjamin Weiman-Kelman; Shaul Raviv; Ernst R. Tamm; Metsada Pasmanik-Chor; Ariel Rinon; Dvir Netanely; Ron Shamir; Arie S. Solomon; Ruth Ashery-Padan Dysfunction of the retinal pigmented epithelium (RPE) results in degeneration of photoreceptors and vision loss and is correlated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (15): 2505–2510.
Published: 1 August 2009
...Peter Westenskow; Stefano Piccolo; Sabine Fuhrmann The retinal pigment epithelium (RPE) consists of a monolayer of cuboidal,pigmented cells that is located between the retina and the choroid. The RPE is vital for growth and function of the vertebrate eye and improper development results...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (24): 4101–4111.
Published: 15 December 2008
... pigment epithelium (RPE). We find that a Wnt reporter transgene and Wnt pathway components are expressed in the dorsal RPE beginning at 14-16 hours post-fertilization. In the absence of Wnt signaling, tbx5 and Bmp genes initiate normal dorsal retinal expression but are not maintained. The expression...
Journal Articles
Journal: Development
Development (2006) 133 (20): 4109–4118.
Published: 15 October 2006
... called Shroom),is sufficient to induce a dramatic apical accumulation of the microtubule-nucleating protein γ-tubulin at the apical surfaces of naïve epithelial cells. Together, our data identify Shroom2 as a central regulator of RPE pigmentation, and suggest that, despite their diverse biological roles...
Journal Articles
Journal: Development
Development (2005) 132 (1): 177–187.
Published: 1 January 2005
... (RPE) progenitors expressing the transcription factor Mitf. Chx10 mutations lead to microphthalmia and impaired neuroretinal proliferation. Mitf mutants have a dorsal RPE-to-neuroretinal phenotypic transformation, indicating that Mitf is a determinant of RPE identity. We report here that Mitf...
Includes: Supplementary data