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Keywords: ROCK
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Journal Articles
Journal: Development
Development (2015) 142 (9): 1639–1650.
Published: 1 May 2015
... in the transverse plane, allowing sufficient time for lumen growth via an osmotic process along the longitudinal dimension. The dynamics of lumen formation is controlled by the TGFβ pathway and ROCK activity. Our findings reveal a TGFβ-ROCK-actomyosin contractility axis that coordinates lumen growth, which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (2): 411–422.
Published: 15 January 2012
... and the basement membrane-mediated signals that regulate coordinated tissue organization are not well defined. Here, we report that Rho kinase (ROCK) controls coordinated tissue organization by restricting basement membrane to the epithelial basal periphery in developing mouse submandibular salivary glands...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (14): 2375–2384.
Published: 15 July 2009
... of mesodermal cells, without which convergence is impaired. Bleb Blebbing Myosin phosphatase Mypt1 (Ppp1r12a) Zebrafish Gastrulation Convergent extension Convergence Amoeboid RhoA Rock Metastasis Gastrulation is a tightly regulated series of cell rearrangements that establishes...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (20): 3333–3343.
Published: 15 October 2008
... branching morphogenesis during early stages of development of the ureteric collecting duct system. Our results further suggest that the RhoA-ROCK pathway, which is activated downstream of plexin B1, mediates these inhibitory morphogenetic effects of Sema4d and suppresses branch-promoting signalling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (17): 2855–2864.
Published: 1 September 2008
...., Hidalgo-Sanchez, M., Fort, P., Backer, S., Popoff,M. R., Gauthier-Rouviere, C. and Bloch-Gallego, E. ( 2004 ). Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1. Development 131 , 2841 -2852. Chimini, G. and Chavrier, P. ( 2000...