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Fatma O. Kok, Andrew Taibi, Sarah J. Wanner, Xiayang Xie, Cara E. Moravec, Crystal E. Love, Victoria E. Prince, Jeff S. Mumm, Howard I. Sirotkin
Development (2012) 139 (20): 3838–3848.
Published: 15 October 2012
.... Mutants progress normally through embryogenesis but many die as larvae (after 12 days). However, some homozygotes reach adulthood and are viable. We utilized an RE1/NRSE transgenic reporter system to dynamically monitor Rest activity. This analysis revealed that Rest is required to repress gene expression...
Includes: Supplementary data