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Keywords: Prostate
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Journal Articles
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Reproductive biology
Journal: Development
Development (2017) 144 (8): 1382–1398.
Published: 15 April 2017
...Roxanne Toivanen; Michael M. Shen Prostate organogenesis is a complex process that is primarily mediated by the presence of androgens and subsequent mesenchyme-epithelial interactions. The investigation of prostate development is partly driven by its potential relevance to prostate cancer...
Journal Articles
Journal: Development
Development (2007) 134 (3): 557–565.
Published: 1 February 2007
...Sheri L. Kuslak; Joshua L. Thielen; Paul C. Marker The mouse seminal vesicle shape (svs) mutation is a spontaneous recessive mutation that causes branching morphogenesis defects in the prostate gland and seminal vesicles. Unlike many other mutations that reduce prostatic and/or seminal vesicle...
Journal Articles
Journal: Development
Development (2005) 132 (15): 3431–3443.
Published: 1 August 2005
... with androgen signaling and controls prostate differentiated response. Here, we show the mouse Foxa1 expression marks the entire embryonic urogenital sinus epithelium (UGE), contrasting with Shh and Foxa2, which are restricted to the basally located cells during prostate budding. The Foxa1-deficient mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (10): 2061–2069.
Published: 15 May 2003
...Kyriakos D. Economides; Mario R. Capecchi The murine prostate is a structure that is made up of four distinct lobes;the dorsal and lateral prostates (often grouped together as the dorsolateral prostate), the anterior (coagulating gland) and the ventral prostate. Previous work has implicated Hox...
Journal Articles
Journal: Development
Development (2002) 129 (8): 1905–1912.
Published: 15 April 2002
...Axel A. Thomson; Barry G. Timms; Lesley Barton; Gerald R. Cunha; Oliver C. Grace We have examined the role that smooth muscle plays during prostatic organogenesis and propose that differentiation of a smooth muscle layer regulates prostatic induction by controlling mesenchymal/epithelial...