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Keywords: Proneural genes
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Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (19): 3332–3342.
Published: 1 October 2015
...Gemma Sian Richards; Fabian Rentzsch Notch signalling, SoxB and Group A bHLH ‘proneuralgenes are conserved regulators of the neurogenic program in many bilaterians. However, the ancestry of their functions and interactions is not well understood. We address this question in the sea anemone...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (2): 295–305.
Published: 15 January 2007
...Bonny B. Millimaki; Elly M. Sweet; Mary S. Dhason; Bruce B. Riley Hair cells of the inner ear develop from an equivalence group marked by expression of the proneural gene Atoh1 . In mouse, Atoh1 is necessary for hair cell differentiation, but its role in specifying the equivalence group (proneural...
Journal Articles
Journal: Development
Development (2006) 133 (9): 1683–1692.
Published: 1 May 2006
... at the Drosophila wing margin have been reported to be unaffected by mutations that remove Achaete and Scute function. Indeed, the proneural gene(s) for these organs is not known. Here, we show that the zinc-finger transcription factor Senseless, together with Daughterless, plays the proneural role for the wing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (3): 495–505.
Published: 1 February 2006
...Julianna Kele; Nicolas Simplicio; Anna L. M. Ferri; Helena Mira; François Guillemot; Ernest Arenas; Siew-Lan Ang Proneural genes are crucial regulators of neurogenesis and subtype specification in many areas of the nervous system; however, their function in dopaminergic neuron development...
Journal Articles
Journal: Development
Development (2006) 133 (3): 507–516.
Published: 1 February 2006
...E. Andersson; J. B. Jensen; M. Parmar; F. Guillemot; A. Björklund Neurogenin 2 ( Ngn2 ) is a proneural gene involved in neuronal differentiation and subtype specification in various regions of the nervous system. In the ventral midbrain, Ngn2 is expressed in a spatiotemporal pattern...
Journal Articles
Journal: Development
Development (2005) 132 (11): 2573–2585.
Published: 1 June 2005
... of neurogenesis many cell cycles later, thereby potentially coordinating axial patterning with control of neuron number and cell fate. * Author for correspondence (e-mail: jnk@phy.ucsf.edu ) 22 3 2005 ©2005. 2005 Zebrafish ath5 ( atoh7 ) Proneural genes Atonal Sonic Hedgehog...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (11): 2639–2648.
Published: 1 June 2002
... inappropriate levels of Ngn1 protein that upregulate genes normally activated by other bHLH genes. This interpretation is consistent with results from two studies in flies of misexpressed atonal ( ato ), a proneural gene required in chordotonal organs (CHO), but not external sensory organs (ESO). Surprisingly...
Journal Articles
Journal: Development
Development (2002) 129 (4): 935–944.
Published: 15 February 2002
... through the activity of the proneural genes. We demonstrate that both signalling and responsive cells are set aside in each tubule primordium from a proneural gene-expressing cluster of cells, in a two-step process. First, a proneural cluster develops within the domain of Wingless-activated, pointedP2...
Journal Articles
Journal: Development
Development (2001) 128 (14): 2673–2688.
Published: 15 July 2001
... phalangioides , and appears thus to be conserved at least among the Araneae. We have identified two basic helix-loop-helix encoding genes – CsASH1 and CsASH2 – that share sequence similarities with proneural genes from other species. Functional analysis of the genes by double-stranded RNA interference revealed...
Journal Articles
Journal: Development
Development (2001) 128 (2): 299–308.
Published: 15 January 2001
...Joaquim Culí; Enrique Martín-Blanco; Juan Modolell ABSTRACT An early step in the development of the large mesothoracic bristles (macrochaetae) of Drosophila is the expression of the proneural genes of the achaete-scute complex (AS-C) in small groups of cells (proneural clusters) of the wing...
Journal Articles
Journal: Development
Development (1998) 125 (23): 4821–4833.
Published: 1 December 1998
... an increase in differentiated bipolar cells. Directed expression of Math5 , but not Xath5 , in Xenopus blastomeres produced an expanded retinal phenotype. We propose that Math5 acts as a proneural gene, but has properties different from its most closely related vertebrate family member, Xath5 . * Author...
Journal Articles
Journal: Development
Development (1997) 124 (22): 4557–4569.
Published: 15 November 1997
...Patrick Blader; Nadine Fischer; Gerard Gradwohl; François Guillemot; Uwe Strähle ABSTRACT Zebrafish neurogenin1 encodes a basic helix-loop-helix protein which shares structural and functional characteristics with proneural genes of Drosophila melanogaster. neurogenin1 is expressed in the early...
Journal Articles
Journal: Development
Development (1996) 122 (12): 4139–4147.
Published: 1 December 1996
...Mehmet E. Dokucu; S. Lawrence Zipursky; Ross L. Cagan ABSTRACT In the developing Drosophila retina, the proneural gene for photoreceptor neurons is atonal , a basic helix-loop-helix transcription factor. Using atonal as a marker for proneural maturation, we examine the stepwise resolution...
Journal Articles
Journal Articles
Journal: Development
Development (1995) 121 (2): 429–438.
Published: 1 February 1995
... that the complex affects gliogenesis indirectly. These observations lead to the hypothesis that glio-genesis is induced by the presence of sensory organ cells, either the precursor or its progeny. 03 11 1994 © 1995 by Company of Biologists 1995 proneural genes gliogenesis PNS Drosophila...