1-20 of 24
Keywords: Primitive endoderm
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal Articles
Journal: Development
Development (2022) 149 (20): dev192310.
Published: 22 August 2022
... established, these two lineages autonomously progress in minimal medium to form an inner pro-amniotic-like cavity surrounded by polarized Epi-like cells covered with visceral endoderm (VE)-like cells. The progression occurs through reciprocal inductions by which the Epi supports the primitive endoderm (PrE...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (21): dev199926.
Published: 5 November 2021
... and primitive endoderm-like cells in mouse embryonic stem cell cultures emerges at the population level through cell-cell communication via a short-range fibroblast growth factor 4 (FGF4) signal. We characterize the molecular and dynamical properties of the communication mechanism and show how it controls both...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (14): dev183079.
Published: 22 July 2020
... Self-organisation Epiblast Primitive endoderm One of the most fundamental questions in biology is: how can one cell, a fertilised zygote, give rise to all of the different cell types found in the adult body? The sequential formation of different types of cells that arrange themselves...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2017) 144 (8): 1450–1461.
Published: 15 April 2017
...Mubeen Goolam; Magdalena Zernicka-Goetz The separation of embryonic from extra-embryonic tissues within the inner cell mass to generate the epiblast (EPI), which will form the new organism, from the primitive endoderm (PE), which will form the yolk sac, is a crucial developmental decision. Here, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (20): 3488–3499.
Published: 15 October 2015
... gene expression. Here, we report that LIF has two distinct roles: it blocks early epiblast (Epi) differentiation, and it supports the expansion of primitive endoderm (PrE)-primed ESCs and PrE in vivo . We find that activation of JAK/STAT signalling downstream of LIF occurs initially throughout the pre...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3637–3648.
Published: 1 October 2014
...Sylvain Bessonnard; Laurane De Mot; Didier Gonze; Manon Barriol; Cynthia Dennis; Albert Goldbeter; Geneviève Dupont; Claire Chazaud During blastocyst formation, inner cell mass (ICM) cells differentiate into either epiblast (Epi) or primitive endoderm (PrE) cells, labeled by Nanog and Gata6...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1001–1010.
Published: 1 March 2014
... and maintenance of embryonic stem cells and for reprogramming somatic cells to pluripotency. In vivo , it prevents the ectopic differentiation of early embryos into trophoblast. Here, we further explore the role of Oct4 in blastocyst formation and specification of epiblast versus primitive endoderm lineages using...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1140–1150.
Published: 1 March 2014
... outer trophectoderm (TE) and internal primitive endoderm (PE) in the blastocyst and subsequently give rise to chorio-allantoic and visceral yolk sac placentae, respectively. We have shown maternal low protein diet exclusively during mouse preimplantation development (Emb-LPD) is sufficient to cause...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (1): 3–14.
Published: 1 January 2012
...Katsuyoshi Takaoka; Hiroshi Hamada The mouse embryo generates multiple cell lineages, as well as its future body axes in the early phase of its development. The early cell fate decisions lead to the generation of three lineages in the pre-implantation embryo: the epiblast, the primitive endoderm...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2010) 137 (23): 3953–3963.
Published: 1 December 2010
...-implantation embryo. Here, we show that Klf5 is required for the formation of the trophectoderm (TE) and the inner cell mass (ICM), and for repressing primitive endoderm (PE) development. Although cell polarity appeared normal, Klf5 mutant embryos arrested at the blastocyst stage and failed to hatch due...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (20): 3361–3372.
Published: 15 October 2010
...Jérôme Artus; Jean-Jacques Panthier; Anna-Katerina Hadjantonakis The inner cell mass (ICM) of the implanting mammalian blastocyst comprises two lineages: the pluripotent epiblast (EPI) and primitive endoderm (PrE). We have identified platelet-derived growth factor receptor alpha (PDGFRα...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (5): 715–724.
Published: 1 March 2010
...Yojiro Yamanaka; Fredrik Lanner; Janet Rossant Primitive endoderm (PE) and epiblast (EPI) are two lineages derived from the inner cell mass (ICM) of the E3.5 blastocyst. Recent studies showed that EPI and PE progenitors expressing the lineage-specific transcriptional factors Nanog and Gata6...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (18): 3081–3091.
Published: 15 September 2008
...Berenika Plusa; Anna Piliszek; Stephen Frankenberg; Jérôme Artus; Anna-Katerina Hadjantonakis The first two lineages to differentiate from a pluripotent cell population during mammalian development are the extraembryonic trophectoderm (TE) and the primitive endoderm (PrE). Whereas the mechanisms...
Includes: Multimedia, Supplementary data